The spatio-temporal regulation of Polo-like kinase 1 in DNA repair

<p>The G2/M cell cycle kinase Polo-like kinase 1 (PLK1) was recently discovered to play an active role in DNA repair by phosphorylating the RAD51 recombinase to aid homologous recombination. This occurs at a much shorter timeframe than the well-characterised downregulation of PLK1 activity via...

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Bibliographic Details
Main Author: Legg, K
Other Authors: Esashi, F
Format: Thesis
Language:English
Published: 2019
Subjects: