YACs, BACs, PACs and MACs: artificial chromosomes as research tools.
Yeast artificial chromosomes (YACs) have become essential research tools as they enable large fragments of DNA to be cloned. In order to overcome several disadvantages of YACs, including chimaerism and instability, several complementary bacterial artificial chromosome (BAC) vectors have been develop...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
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Elsevier
1994
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| _version_ | 1797059200964100096 |
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| author | Monaco, A Larin, Z |
| author_facet | Monaco, A Larin, Z |
| author_sort | Monaco, A |
| collection | OXFORD |
| description | Yeast artificial chromosomes (YACs) have become essential research tools as they enable large fragments of DNA to be cloned. In order to overcome several disadvantages of YACs, including chimaerism and instability, several complementary bacterial artificial chromosome (BAC) vectors have been developed. More recently, attempts are being made to construct artificial chromosomes in mammalian cells (MACs). |
| first_indexed | 2024-03-06T20:00:50Z |
| format | Journal article |
| id | oxford-uuid:273c7b3b-6c1a-4025-ad94-f2479def2160 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T20:00:50Z |
| publishDate | 1994 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oxford-uuid:273c7b3b-6c1a-4025-ad94-f2479def21602022-03-26T12:05:47ZYACs, BACs, PACs and MACs: artificial chromosomes as research tools.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:273c7b3b-6c1a-4025-ad94-f2479def2160EnglishSymplectic Elements at OxfordElsevier1994Monaco, ALarin, ZYeast artificial chromosomes (YACs) have become essential research tools as they enable large fragments of DNA to be cloned. In order to overcome several disadvantages of YACs, including chimaerism and instability, several complementary bacterial artificial chromosome (BAC) vectors have been developed. More recently, attempts are being made to construct artificial chromosomes in mammalian cells (MACs). |
| spellingShingle | Monaco, A Larin, Z YACs, BACs, PACs and MACs: artificial chromosomes as research tools. |
| title | YACs, BACs, PACs and MACs: artificial chromosomes as research tools. |
| title_full | YACs, BACs, PACs and MACs: artificial chromosomes as research tools. |
| title_fullStr | YACs, BACs, PACs and MACs: artificial chromosomes as research tools. |
| title_full_unstemmed | YACs, BACs, PACs and MACs: artificial chromosomes as research tools. |
| title_short | YACs, BACs, PACs and MACs: artificial chromosomes as research tools. |
| title_sort | yacs bacs pacs and macs artificial chromosomes as research tools |
| work_keys_str_mv | AT monacoa yacsbacspacsandmacsartificialchromosomesasresearchtools AT larinz yacsbacspacsandmacsartificialchromosomesasresearchtools |