SAMHD1 is mutated recurrently in chronic lymphocytic leukemia and is involved in response to DNA damage.

SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase and a nuclease that restricts HIV-1 in noncycling cells. Germ-line mutations in SAMHD1 have been described in patients with Aicardi-Goutières syndrome (AGS), a congenital autoimmune disease. In a previous longitudinal whole genome sequenci...

Täydet tiedot

Bibliografiset tiedot
Päätekijät:	Clifford, R, Louis, T, Robbe, P, Ackroyd, S, Burns, A, Timbs, A, Wright Colopy, G, Dreau, H, Sigaux, F, Judde, J, Rotger, M, Telenti, A, Lin, Y, Pasero, P, Maelfait, J, Titsias, M, Cohen, DR, Henderson, S, Ross, M, Bentley, D, Hillmen, P, Pettitt, A, Rehwinkel, J, Knight, S, Taylor, J
Aineistotyyppi:	Journal article
Kieli:	English
Julkaistu:	American Society of Hematology 2014

SAMHD1 is mutated recurrently in chronic lymphocytic leukemia and is involved in response to DNA damage.

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