Blood and immune development in human fetal bone marrow and Down syndrome

Haematopoiesis in the bone marrow (BM) maintains blood and immune cell production throughout postnatal life. Haematopoiesis first emerges in human BM at 11–12 weeks after conception1,2, yet almost nothing is known about how fetal BM (FBM) evolves to meet the highly specialized needs of the fetus and...

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Main Authors:	Jardine, L, Webb, S, Goh, I, Quiroga Londoño, M, Reynolds, G, Mather, M, Olabi, B, Stephenson, E, Botting, RA, Horsfall, D, Engelbert, J, Maunder, D, Mende, N, Murnane, C, Dann, E, McGrath, J, King, H, Kucinski, I, Queen, R, Carey, CD, Shrubsole, C, Poyner, E, Acres, M, Jones, C, Ness, T, Coulthard, R, Elliott, N, O’Byrne, S, Haltalli, MLR, Lawrence, JE, Lisgo, S, Balogh, P, Meyer, KB, Prigmore, E, Ambridge, K, Jain, MS, Efremova, M, Pickard, K, Creasey, T, Bacardit, J, Henderson, D, Coxhead, J, Filby, A, Hussain, R, Dixon, D, McDonald, D, Popescu, D-M, Kowalczyk, MS, Li, B, Ashenberg, O, Roy, A, Et al.
Format:	Journal article
Sprog:	English
Udgivet:	Springer Nature 2021

Blood and immune development in human fetal bone marrow and Down syndrome

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