PIP2 stabilises active states of GPCRs and enhances the selectivity
G protein-coupled receptors (GPCRs) are involved in many physiological processes and are therefore key drug targets 1. Despite detailed structural information however the effects of lipids on the receptors themselves, or on their downstream coupling to G proteins, are ill defined. Here we use native...
| Những tác giả chính: | , , , , , , , , , , , , , , |
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| Định dạng: | Journal article |
| Được phát hành: |
Nature Publishing Group
2018
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