A novel Pkhd1 mutation interacts with the nonobese 1Diabetic genetic background to cause autoimmune cholangitis

A novel Pkhd1 mutation interacts with the nonobese 1Diabetic genetic background to cause autoimmune cholangitis

We previously reported that NOD.c3c4 mice develop spontaneous autoimmune biliary disease (ABD) with anti-mitochondrial Abs, histopathological lesions, and autoimmune T lymphocytes similar to human primary biliary cholangitis. In this article, we demonstrate that ABD in NOD.c3c4 and related NOD ABD s...

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Bibliographic Details
Main Authors:	Huang, W, Rainbow, DB, Wu, Y, Adams, D, Shivakumar, P, Kottyan, L, Karns, R, Aronow, B, Bezerra, J, Gershwin, ME, Peterson, LB, Wicker, LS, Ridgway, WM
Format:	Journal article
Language:	English
Published:	American Association of Immunologists 2017

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