DELTEX E3 ligases ubiquitylate ADP-ribosyl modification on protein substrates

DELTEX E3 ligases ubiquitylate ADP-ribosyl modification on protein substrates

Ubiquitylation had been considered limited to protein lysine residues, but other substrates have recently emerged. Here, we show that DELTEX E3 ligases specifically target the 3' hydroxyl of the adenosine diphosphate (ADP)-ribosyl moiety that can be linked to a protein, thus generating a hybrid...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Zhu, K, Suskiewicz, MJ, Hloušek-Kasun, A, Meudal, H, Mikoč, A, Aucagne, V, Ahel, D, Ahel, I
التنسيق: Journal article
اللغة:English
منشور في: American Association for the Advancement of Science 2022

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