Neuromyelitis optica IgG causes placental inflammation and fetal death.

Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the CNS and affects women of childbearing age. Most patients with NMO have circulating Abs, termed NMO-IgG, against the astrocytic water channel protein aquaporin-4. In the CNS, NMO-IgG causes complement-mediated astrocyte damage...

詳細記述

書誌詳細
主要な著者: Saadoun, S, Waters, P, Leite, M, Bennett, J, Vincent, A, Papadopoulos, M
フォーマット: Journal article
言語:English
出版事項: 2013