Targeting the bacterial SOS response for new antimicrobial agents: drug targets, molecular mechanisms and inhibitors

Targeting the bacterial SOS response for new antimicrobial agents: drug targets, molecular mechanisms and inhibitors

Antimicrobial resistance is a pressing threat to global health, with multidrug-resistant pathogens becoming increasingly prevalent. The bacterial SOS pathway functions in response to DNA damage that occurs during infection, initiating several pro-survival and resistance mechanisms, such as DNA repai...

書誌詳細
第一著者:	Lanyon-Hogg, T
フォーマット:	Journal article
言語:	English
出版事項:	Future Science 2021

類似資料

Staphylococcus aureus SOS response: Activation, impact, and drug targets
著者:: Kaiying Cheng, 等
出版事項: (2024-09-01)

Development of an inhibitor of the mutagenic SOS response that suppresses the evolution of quinolone antibiotic resistance
著者:: Bradbury, JD, 等
出版事項: (2024)

Role of Extracellular DNA in Bacterial Response to SOS-Inducing Drugs
著者:: John K. Crane, 等
出版事項: (2023-03-01)

Targeting evolution of antibiotic resistance by SOS response inhibition
著者:: Alexander Yakimov, 等
出版事項: (2021-01-01)

Sending out an SOS - the bacterial DNA damage response
著者:: Marco A. Lima-Noronha, 等
出版事項: (2022-10-01)

Novel Targets and Mechanisms in Antimicrobial Drug Discovery
著者:: Donatella Tondi
出版事項: (2021-02-01)

Phagosomal granulocytic ROS in septic patients induce the bacterial SOS response
著者:: Stecy Chollet, 等
出版事項: (2024-06-01)

New Molecular Targets for Antidepressant Drugs
著者:: Johannes Kornhuber, 等
出版事項: (2021-09-01)

Anthraquinones as Inhibitors of SOS RAS-GEF Activity
著者:: Alberto Fernández-Medarde, 等
出版事項: (2021-07-01)

After 30 years of study, the bacterial SOS response still surprises us.
出版事項: (2005-07-01)

After 30 years of study, the bacterial SOS response still surprises us.
著者:: Bénédicte Michel
出版事項: (2005-07-01)

Synthesis, Physicochemical Properties and Molecular Docking of New Benzothiazole Derivatives as Antimicrobial Agents Targeting DHPS Enzyme
著者:: Rasha A. Azzam, 等
出版事項: (2022-12-01)

Molecular Mechanisms of Glucocorticoid Resistance in Corticotropinomas: New Developments and Drug Targets
著者:: Denis Ciato, 等
出版事項: (2020-01-01)

Bacterial SOS May Be the Key to Combating Antibiotic Resistance.
出版事項: (2005-06-01)

Focal Targeting of the Bacterial Envelope by Antimicrobial Peptides
著者:: Rafi eRashid, 等
出版事項: (2016-06-01)

Nano-MOFs as targeted drug delivery agents to combat antibiotic-resistant bacterial infections
著者:: Saleh A. Ahmed, 等
出版事項: (2020-12-01)

Antibiotic drugs targeting bacterial RNAs
著者:: Weiling Hong, 等
出版事項: (2014-08-01)

Molecular targets to develop future antimicrobials
著者:: Mohammed Z. Al-Khayyat
出版事項: (2019-06-01)

Targeting of PBP1 by β-lactams determines recA/SOS response activation in heterogeneous MRSA clinical strains.
著者:: Konrad B Plata, 等
出版事項: (2013-01-01)

New Insight into the Molecular Drug Target of Diabetic Nephropathy
著者:: Vivian Soetikno, 等
出版事項: (2014-01-01)

Targeted Therapy: Attacking Cancer with Molecular and Immunological Targeted Agents
著者:: Gail M Wilkes
出版事項: (2018-01-01)

Metabolic network analysis-based identification of antimicrobial drug targets in category A bioterrorism agents.
著者:: Yong-Yeol Ahn, 等
出版事項: (2014-01-01)

Bacterial Protein Tyrosine Phosphatases as Possible Targets for Antimicrobial Therapies in Response to Antibiotic Resistance
著者:: Alicja Kuban-Jankowska, 等
出版事項: (2022-12-01)

Targeted Contrast Agents for Molecular MRI
著者:: Sara Lacerda
出版事項: (2018-12-01)

Design of Photosensitizing Agents for Targeted Antimicrobial Photodynamic Therapy
著者:: Maxime Klausen, 等
出版事項: (2020-11-01)

Recent Advances in Histidine Kinase-Targeted Antimicrobial Agents
著者:: Hongtong Chen, 等
出版事項: (2022-07-01)

SOS Mulher
著者:: Maria das Dores Campos Machado
出版事項: (1999-12-01)

Bacterial Resistance to Antimicrobial Agents
著者:: Manuel F. Varela, 等
出版事項: (2021-05-01)

Drug-Clinical Agent Molecular Hybrid: Synthesis of Diaryl(trifluoromethyl)pyrazoles as Tubulin Targeting Anticancer Agents
著者:: Neha Hura, 等
出版事項: (2018-02-01)

New drug target identification in Vibrio vulnificus by subtractive genome analysis and their inhibitors through molecular docking and molecular dynamics simulations
著者:: Bader S. Alotaibi, 等
出版事項: (2023-07-01)

YY1 downregulation underlies therapeutic response to molecular targeted agents
著者:: Shichao Zhou, 等
出版事項: (2024-11-01)

Molecular-Targeted Drugs in Rheumatology
著者:: Eiichi Tanaka
出版事項: (2023-12-01)

Stochastic analysis of the SOS response in Escherichia coli.
著者:: Yishai Shimoni, 等
出版事項: (2009-01-01)

Novel antimony-based antimicrobial drug targets membranes of Gram-positive and Gram-negative bacterial pathogens
著者:: Tarosha Salpadoru, 等
出版事項: (2024-06-01)

Editorial: The molecular mechanisms and potential drug targets for remyelination and neuroregeneration
著者:: Aleksandra Rutkowska, 等
出版事項: (2023-11-01)

Prospective virtual screening combined with bio-molecular simulation enabled identification of new inhibitors for the KRAS drug target
著者:: Amar Ajmal, 等
出版事項: (2024-03-01)

Toxin Gene Expression by Shiga Toxin-Producing Escherichia coli: the Role of Antibiotics and the Bacterial SOS Response
著者:: Patrick T. Kimmitt, 等
出版事項: (2000-10-01)

Biology before the SOS Response—DNA Damage Mechanisms at Chromosome Fragile Sites
著者:: Devon M. Fitzgerald, 等
出版事項: (2021-09-01)

Diarylureas: Repositioning from Antitumor to Antimicrobials or Multi-Target Agents against New Pandemics
著者:: Alessia Catalano, 等
出版事項: (2021-01-01)

Bacterial signal transduction : networks and drug targets /
著者:: Utsumi, Ryutaro
出版事項: (2008)