Targeting the bacterial SOS response for new antimicrobial agents: drug targets, molecular mechanisms and inhibitors

Targeting the bacterial SOS response for new antimicrobial agents: drug targets, molecular mechanisms and inhibitors

Antimicrobial resistance is a pressing threat to global health, with multidrug-resistant pathogens becoming increasingly prevalent. The bacterial SOS pathway functions in response to DNA damage that occurs during infection, initiating several pro-survival and resistance mechanisms, such as DNA repai...

Bibliográfalaš dieđut
Váldodahkki:	Lanyon-Hogg, T
Materiálatiipa:	Journal article
Giella:	English
Almmustuhtton:	Future Science 2021

Geahča maid

Staphylococcus aureus SOS response: Activation, impact, and drug targets
Dahkki: Kaiying Cheng, et al.
Almmustuhtton: (2024-09-01)

Development of an inhibitor of the mutagenic SOS response that suppresses the evolution of quinolone antibiotic resistance
Dahkki: Bradbury, JD, et al.
Almmustuhtton: (2024)

Role of Extracellular DNA in Bacterial Response to SOS-Inducing Drugs
Dahkki: John K. Crane, et al.
Almmustuhtton: (2023-03-01)

Targeting evolution of antibiotic resistance by SOS response inhibition
Dahkki: Alexander Yakimov, et al.
Almmustuhtton: (2021-01-01)

Sending out an SOS - the bacterial DNA damage response
Dahkki: Marco A. Lima-Noronha, et al.
Almmustuhtton: (2022-10-01)

Novel Targets and Mechanisms in Antimicrobial Drug Discovery
Dahkki: Donatella Tondi
Almmustuhtton: (2021-02-01)

Phagosomal granulocytic ROS in septic patients induce the bacterial SOS response
Dahkki: Stecy Chollet, et al.
Almmustuhtton: (2024-06-01)

New Molecular Targets for Antidepressant Drugs
Dahkki: Johannes Kornhuber, et al.
Almmustuhtton: (2021-09-01)

Anthraquinones as Inhibitors of SOS RAS-GEF Activity
Dahkki: Alberto Fernández-Medarde, et al.
Almmustuhtton: (2021-07-01)

After 30 years of study, the bacterial SOS response still surprises us.
Almmustuhtton: (2005-07-01)

After 30 years of study, the bacterial SOS response still surprises us.
Dahkki: Bénédicte Michel
Almmustuhtton: (2005-07-01)

Synthesis, Physicochemical Properties and Molecular Docking of New Benzothiazole Derivatives as Antimicrobial Agents Targeting DHPS Enzyme
Dahkki: Rasha A. Azzam, et al.
Almmustuhtton: (2022-12-01)

Molecular Mechanisms of Glucocorticoid Resistance in Corticotropinomas: New Developments and Drug Targets
Dahkki: Denis Ciato, et al.
Almmustuhtton: (2020-01-01)

Bacterial SOS May Be the Key to Combating Antibiotic Resistance.
Almmustuhtton: (2005-06-01)

Focal Targeting of the Bacterial Envelope by Antimicrobial Peptides
Dahkki: Rafi eRashid, et al.
Almmustuhtton: (2016-06-01)

Nano-MOFs as targeted drug delivery agents to combat antibiotic-resistant bacterial infections
Dahkki: Saleh A. Ahmed, et al.
Almmustuhtton: (2020-12-01)

Antibiotic drugs targeting bacterial RNAs
Dahkki: Weiling Hong, et al.
Almmustuhtton: (2014-08-01)

Molecular targets to develop future antimicrobials
Dahkki: Mohammed Z. Al-Khayyat
Almmustuhtton: (2019-06-01)

Targeting of PBP1 by β-lactams determines recA/SOS response activation in heterogeneous MRSA clinical strains.
Dahkki: Konrad B Plata, et al.
Almmustuhtton: (2013-01-01)

New Insight into the Molecular Drug Target of Diabetic Nephropathy
Dahkki: Vivian Soetikno, et al.
Almmustuhtton: (2014-01-01)

Targeted Therapy: Attacking Cancer with Molecular and Immunological Targeted Agents
Dahkki: Gail M Wilkes
Almmustuhtton: (2018-01-01)

Metabolic network analysis-based identification of antimicrobial drug targets in category A bioterrorism agents.
Dahkki: Yong-Yeol Ahn, et al.
Almmustuhtton: (2014-01-01)

Bacterial Protein Tyrosine Phosphatases as Possible Targets for Antimicrobial Therapies in Response to Antibiotic Resistance
Dahkki: Alicja Kuban-Jankowska, et al.
Almmustuhtton: (2022-12-01)

Targeted Contrast Agents for Molecular MRI
Dahkki: Sara Lacerda
Almmustuhtton: (2018-12-01)

Design of Photosensitizing Agents for Targeted Antimicrobial Photodynamic Therapy
Dahkki: Maxime Klausen, et al.
Almmustuhtton: (2020-11-01)

Recent Advances in Histidine Kinase-Targeted Antimicrobial Agents
Dahkki: Hongtong Chen, et al.
Almmustuhtton: (2022-07-01)

SOS Mulher
Dahkki: Maria das Dores Campos Machado
Almmustuhtton: (1999-12-01)

Bacterial Resistance to Antimicrobial Agents
Dahkki: Manuel F. Varela, et al.
Almmustuhtton: (2021-05-01)

Drug-Clinical Agent Molecular Hybrid: Synthesis of Diaryl(trifluoromethyl)pyrazoles as Tubulin Targeting Anticancer Agents
Dahkki: Neha Hura, et al.
Almmustuhtton: (2018-02-01)

New drug target identification in Vibrio vulnificus by subtractive genome analysis and their inhibitors through molecular docking and molecular dynamics simulations
Dahkki: Bader S. Alotaibi, et al.
Almmustuhtton: (2023-07-01)

YY1 downregulation underlies therapeutic response to molecular targeted agents
Dahkki: Shichao Zhou, et al.
Almmustuhtton: (2024-11-01)

Molecular-Targeted Drugs in Rheumatology
Dahkki: Eiichi Tanaka
Almmustuhtton: (2023-12-01)

Stochastic analysis of the SOS response in Escherichia coli.
Dahkki: Yishai Shimoni, et al.
Almmustuhtton: (2009-01-01)

Novel antimony-based antimicrobial drug targets membranes of Gram-positive and Gram-negative bacterial pathogens
Dahkki: Tarosha Salpadoru, et al.
Almmustuhtton: (2024-06-01)

Editorial: The molecular mechanisms and potential drug targets for remyelination and neuroregeneration
Dahkki: Aleksandra Rutkowska, et al.
Almmustuhtton: (2023-11-01)

Prospective virtual screening combined with bio-molecular simulation enabled identification of new inhibitors for the KRAS drug target
Dahkki: Amar Ajmal, et al.
Almmustuhtton: (2024-03-01)

Toxin Gene Expression by Shiga Toxin-Producing Escherichia coli: the Role of Antibiotics and the Bacterial SOS Response
Dahkki: Patrick T. Kimmitt, et al.
Almmustuhtton: (2000-10-01)

Biology before the SOS Response—DNA Damage Mechanisms at Chromosome Fragile Sites
Dahkki: Devon M. Fitzgerald, et al.
Almmustuhtton: (2021-09-01)

Diarylureas: Repositioning from Antitumor to Antimicrobials or Multi-Target Agents against New Pandemics
Dahkki: Alessia Catalano, et al.
Almmustuhtton: (2021-01-01)

Bacterial signal transduction : networks and drug targets /
Dahkki: Utsumi, Ryutaro
Almmustuhtton: (2008)