DNA damage responses to loss of telomere integrity

DNA damage responses to loss of telomere integrity

<p>Linear genomes end in characteristic structures consisting of repetitive DNA and proteins: the telomeres. These play two critical roles: on one hand they avoid the of loss of genetic information due to the incomplete replication of the chromosome ends and on the other, they provide capping...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awdur:	Carlos, AR
Awduron Eraill:	Tarsounas, M
Fformat:	Traethawd Ymchwil
Iaith:	English
Cyhoeddwyd:	2013
Pynciau:	DNA damage signalling Biology (medical sciences)

Eitemau Tebyg

The role of Wee1 in the hypoxia-induced DNA damage response and its potential as a therapeutic target
gan: O'Brien, EM
Cyhoeddwyd: (2012)

Base excision repair of radiation-induced DNA damage in mammalian cells
gan: Cooper, S, et al.
Cyhoeddwyd: (2013)

Molecular mechanisms of ARF regulation in response to DNA damage
gan: Orlando, G
Cyhoeddwyd: (2014)

Study of DNA double strand break repair in Dictyostelium discoideum
gan: Lempidaki, S
Cyhoeddwyd: (2012)

Systematic Analysis of the DNA Damage Response Network in Telomere Defective Budding Yeast
gan: Eva-Maria Holstein, et al.
Cyhoeddwyd: (2017-07-01)

BRCA1 in the DNA damage response and at telomeres
gan: Eliot Michael Rosen
Cyhoeddwyd: (2013-06-01)

Hypoxia-induced chromatin changes and ATM signalling
gan: Olcina del Molino, M
Cyhoeddwyd: (2014)

Investigation into the regulatory mechanism of BRCA2 stability
gan: Gruber, C
Cyhoeddwyd: (2013)

DNA damage regulation and its role in drug-related phenotypes in the malaria parasites
gan: Gupta, Devendra Kumar, et al.
Cyhoeddwyd: (2018)

Novel regulation of SRC family kinase signalling by RASSF1 isoforms
gan: Scrace, SF
Cyhoeddwyd: (2013)

The role of ubiquitylation in regulating apurinic/apyrimidinic endonuclease 1
gan: Meisenberg, C
Cyhoeddwyd: (2012)

Links between the unfolded protein response and the DNA damage response in hypoxia
gan: Ma, TS
Cyhoeddwyd: (2022)

Signalling inhibition by ponatinib disrupts productive alternative lengthening of telomeres (ALT)
gan: Kusuma, Frances Karla, et al.
Cyhoeddwyd: (2023)

Selective targeting of homologous recombination deficiency
gan: Zimmer, J
Cyhoeddwyd: (2014)

The three methyls: the function and therapeutic potential of histone H3K36 trimethylation
gan: Pfister, SX
Cyhoeddwyd: (2014)

Impact of diffused versus vasculature targeted DNA damage on the heart of mice depleted of telomeric factor Ft1
gan: La Torre, Mattia, et al.
Cyhoeddwyd: (2024)

Telomere maintenance and the DNA damage response: a paradoxical alliance
gan: Ashley Harman, et al.
Cyhoeddwyd: (2024-10-01)

The multifaceted world of the DNA damage response
gan: Antonio ePorro
Cyhoeddwyd: (2016-05-01)

Preserving Yeast Genetic Heritage through DNA Damage Checkpoint Regulation and Telomere Maintenance
gan: Huilin Zhou, et al.
Cyhoeddwyd: (2012-10-01)

Editorial: Proceedings From ACCM19: Cell Cycle, DNA Damage Response and Telomeres
gan: Andrew Burgess, et al.
Cyhoeddwyd: (2020-09-01)

Membrane potential-dependent uptake of cationic oligoimidazolium mediates bacterial DNA damage and death
gan: Yong, Melvin, et al.
Cyhoeddwyd: (2023)

Unveiling novel participants in the DNA damage response
gan: Li, S
Cyhoeddwyd: (2024)

Telomere-related DNA damage response pathways in cancer therapy: prospective targets
gan: Liting Gu, et al.
Cyhoeddwyd: (2024-06-01)

DNA damage and mutation. Types of DNA damage
gan: Stoyan Chakarov, et al.
Cyhoeddwyd: (2014-02-01)

DNA damage checkpoint adaptation genes are required for division of cells harbouring eroded telomeres
gan: Sofiane Y. Mersaoui, et al.
Cyhoeddwyd: (2015-09-01)

DNA Damage Response Pathways in Dinoflagellates
gan: Chongping Li, et al.
Cyhoeddwyd: (2019-07-01)

Interactions between the DNA Damage Response and the Telomere Complex in Carcinogenesis: A Hypothesis
gan: Antonio Torres-Montaner
Cyhoeddwyd: (2023-09-01)

Real-time studies of DNA repair kinetics following low-LET short-pulse electron radiation
gan: Mendes de Oliveira Martins, CD
Cyhoeddwyd: (2014)

The DNA damage response in mammalian oocytes
gan: John eCarroll, et al.
Cyhoeddwyd: (2013-06-01)

Development of bioreductive inhibitors of checkpoint kinase 1 to target hypoxic tumours
gan: Körner, C
Cyhoeddwyd: (2015)

The role of DNA polymerase eta in determining cellular responses to chemo-radiation treatment
gan: Nicolay, N
Cyhoeddwyd: (2013)

MiR-215 regulates differentiation in colorectal cancer stem cells
gan: Jones, M
Cyhoeddwyd: (2014)

The role of LATS1 in DNA damage signalling
gan: Latusek, R
Cyhoeddwyd: (2012)

Development of clinical biomarkers of DNA double strand breaks for cancer care
gan: Shah, K
Cyhoeddwyd: (2012)

An analysis of the S. cerevisiae RMI1 gene
gan: Ashton, TM
Cyhoeddwyd: (2010)

New research on DNA damage /
gan: Kimura, Honoka, et al.
Cyhoeddwyd: (2008)

The chemical biology of DNA damage /
gan: Geacintov, Nicholas E., 1935-, et al.
Cyhoeddwyd: (2010)

Structural basis of G-quadruplex DNA recognition by the yeast telomeric protein Rap1
gan: Traczyk, Anna, et al.
Cyhoeddwyd: (2020)

The Role of MicroRNA in DNA Damage Response
gan: Yongxin Li, et al.
Cyhoeddwyd: (2022-05-01)

Histone post-translational modification and the DNA damage response
gan: Haoyun Song, et al.
Cyhoeddwyd: (2023-07-01)