DNA damage responses to loss of telomere integrity

DNA damage responses to loss of telomere integrity

<p>Linear genomes end in characteristic structures consisting of repetitive DNA and proteins: the telomeres. These play two critical roles: on one hand they avoid the of loss of genetic information due to the incomplete replication of the chromosome ends and on the other, they provide capping...

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Bibliografiske detaljer
Hovedforfatter:	Carlos, AR
Andre forfattere:	Tarsounas, M
Format:	Thesis
Sprog:	English
Udgivet:	2013
Fag:	DNA damage signalling Biology (medical sciences)

Lignende værker

The role of Wee1 in the hypoxia-induced DNA damage response and its potential as a therapeutic target
af: O'Brien, EM
Udgivet: (2012)

Base excision repair of radiation-induced DNA damage in mammalian cells
af: Cooper, S, et al.
Udgivet: (2013)

Molecular mechanisms of ARF regulation in response to DNA damage
af: Orlando, G
Udgivet: (2014)

Study of DNA double strand break repair in Dictyostelium discoideum
af: Lempidaki, S
Udgivet: (2012)

Systematic Analysis of the DNA Damage Response Network in Telomere Defective Budding Yeast
af: Eva-Maria Holstein, et al.
Udgivet: (2017-07-01)

BRCA1 in the DNA damage response and at telomeres
af: Eliot Michael Rosen
Udgivet: (2013-06-01)

Hypoxia-induced chromatin changes and ATM signalling
af: Olcina del Molino, M
Udgivet: (2014)

Investigation into the regulatory mechanism of BRCA2 stability
af: Gruber, C
Udgivet: (2013)

DNA damage regulation and its role in drug-related phenotypes in the malaria parasites
af: Gupta, Devendra Kumar, et al.
Udgivet: (2018)

Novel regulation of SRC family kinase signalling by RASSF1 isoforms
af: Scrace, SF
Udgivet: (2013)

The role of ubiquitylation in regulating apurinic/apyrimidinic endonuclease 1
af: Meisenberg, C
Udgivet: (2012)

Links between the unfolded protein response and the DNA damage response in hypoxia
af: Ma, TS
Udgivet: (2022)

Signalling inhibition by ponatinib disrupts productive alternative lengthening of telomeres (ALT)
af: Kusuma, Frances Karla, et al.
Udgivet: (2023)

Selective targeting of homologous recombination deficiency
af: Zimmer, J
Udgivet: (2014)

The three methyls: the function and therapeutic potential of histone H3K36 trimethylation
af: Pfister, SX
Udgivet: (2014)

Impact of diffused versus vasculature targeted DNA damage on the heart of mice depleted of telomeric factor Ft1
af: La Torre, Mattia, et al.
Udgivet: (2024)

Telomere maintenance and the DNA damage response: a paradoxical alliance
af: Ashley Harman, et al.
Udgivet: (2024-10-01)

The multifaceted world of the DNA damage response
af: Antonio ePorro
Udgivet: (2016-05-01)

Preserving Yeast Genetic Heritage through DNA Damage Checkpoint Regulation and Telomere Maintenance
af: Huilin Zhou, et al.
Udgivet: (2012-10-01)

Editorial: Proceedings From ACCM19: Cell Cycle, DNA Damage Response and Telomeres
af: Andrew Burgess, et al.
Udgivet: (2020-09-01)

Membrane potential-dependent uptake of cationic oligoimidazolium mediates bacterial DNA damage and death
af: Yong, Melvin, et al.
Udgivet: (2023)

Unveiling novel participants in the DNA damage response
af: Li, S
Udgivet: (2024)

Telomere-related DNA damage response pathways in cancer therapy: prospective targets
af: Liting Gu, et al.
Udgivet: (2024-06-01)

DNA damage and mutation. Types of DNA damage
af: Stoyan Chakarov, et al.
Udgivet: (2014-02-01)

DNA damage checkpoint adaptation genes are required for division of cells harbouring eroded telomeres
af: Sofiane Y. Mersaoui, et al.
Udgivet: (2015-09-01)

DNA Damage Response Pathways in Dinoflagellates
af: Chongping Li, et al.
Udgivet: (2019-07-01)

Interactions between the DNA Damage Response and the Telomere Complex in Carcinogenesis: A Hypothesis
af: Antonio Torres-Montaner
Udgivet: (2023-09-01)

Real-time studies of DNA repair kinetics following low-LET short-pulse electron radiation
af: Mendes de Oliveira Martins, CD
Udgivet: (2014)

The DNA damage response in mammalian oocytes
af: John eCarroll, et al.
Udgivet: (2013-06-01)

Development of bioreductive inhibitors of checkpoint kinase 1 to target hypoxic tumours
af: Körner, C
Udgivet: (2015)

The role of DNA polymerase eta in determining cellular responses to chemo-radiation treatment
af: Nicolay, N
Udgivet: (2013)

MiR-215 regulates differentiation in colorectal cancer stem cells
af: Jones, M
Udgivet: (2014)

The role of LATS1 in DNA damage signalling
af: Latusek, R
Udgivet: (2012)

Development of clinical biomarkers of DNA double strand breaks for cancer care
af: Shah, K
Udgivet: (2012)

An analysis of the S. cerevisiae RMI1 gene
af: Ashton, TM
Udgivet: (2010)

New research on DNA damage /
af: Kimura, Honoka, et al.
Udgivet: (2008)

The chemical biology of DNA damage /
af: Geacintov, Nicholas E., 1935-, et al.
Udgivet: (2010)

Structural basis of G-quadruplex DNA recognition by the yeast telomeric protein Rap1
af: Traczyk, Anna, et al.
Udgivet: (2020)

The Role of MicroRNA in DNA Damage Response
af: Yongxin Li, et al.
Udgivet: (2022-05-01)

Histone post-translational modification and the DNA damage response
af: Haoyun Song, et al.
Udgivet: (2023-07-01)