DNA damage responses to loss of telomere integrity

DNA damage responses to loss of telomere integrity

<p>Linear genomes end in characteristic structures consisting of repetitive DNA and proteins: the telomeres. These play two critical roles: on one hand they avoid the of loss of genetic information due to the incomplete replication of the chromosome ends and on the other, they provide capping...

Полное описание

Библиографические подробности
Главный автор:	Carlos, AR
Другие авторы:	Tarsounas, M
Формат:	Диссертация
Язык:	English
Опубликовано:	2013
Предметы:	DNA damage signalling Biology (medical sciences)

Схожие документы

The role of Wee1 in the hypoxia-induced DNA damage response and its potential as a therapeutic target
по: O'Brien, EM
Опубликовано: (2012)

Base excision repair of radiation-induced DNA damage in mammalian cells
по: Cooper, S, и др.
Опубликовано: (2013)

Molecular mechanisms of ARF regulation in response to DNA damage
по: Orlando, G
Опубликовано: (2014)

Study of DNA double strand break repair in Dictyostelium discoideum
по: Lempidaki, S
Опубликовано: (2012)

Systematic Analysis of the DNA Damage Response Network in Telomere Defective Budding Yeast
по: Eva-Maria Holstein, и др.
Опубликовано: (2017-07-01)

BRCA1 in the DNA damage response and at telomeres
по: Eliot Michael Rosen
Опубликовано: (2013-06-01)

Hypoxia-induced chromatin changes and ATM signalling
по: Olcina del Molino, M
Опубликовано: (2014)

Investigation into the regulatory mechanism of BRCA2 stability
по: Gruber, C
Опубликовано: (2013)

DNA damage regulation and its role in drug-related phenotypes in the malaria parasites
по: Gupta, Devendra Kumar, и др.
Опубликовано: (2018)

Novel regulation of SRC family kinase signalling by RASSF1 isoforms
по: Scrace, SF
Опубликовано: (2013)

The role of ubiquitylation in regulating apurinic/apyrimidinic endonuclease 1
по: Meisenberg, C
Опубликовано: (2012)

Links between the unfolded protein response and the DNA damage response in hypoxia
по: Ma, TS
Опубликовано: (2022)

Signalling inhibition by ponatinib disrupts productive alternative lengthening of telomeres (ALT)
по: Kusuma, Frances Karla, и др.
Опубликовано: (2023)

Selective targeting of homologous recombination deficiency
по: Zimmer, J
Опубликовано: (2014)

The three methyls: the function and therapeutic potential of histone H3K36 trimethylation
по: Pfister, SX
Опубликовано: (2014)

Impact of diffused versus vasculature targeted DNA damage on the heart of mice depleted of telomeric factor Ft1
по: La Torre, Mattia, и др.
Опубликовано: (2024)

Telomere maintenance and the DNA damage response: a paradoxical alliance
по: Ashley Harman, и др.
Опубликовано: (2024-10-01)

The multifaceted world of the DNA damage response
по: Antonio ePorro
Опубликовано: (2016-05-01)

Preserving Yeast Genetic Heritage through DNA Damage Checkpoint Regulation and Telomere Maintenance
по: Huilin Zhou, и др.
Опубликовано: (2012-10-01)

Editorial: Proceedings From ACCM19: Cell Cycle, DNA Damage Response and Telomeres
по: Andrew Burgess, и др.
Опубликовано: (2020-09-01)

Membrane potential-dependent uptake of cationic oligoimidazolium mediates bacterial DNA damage and death
по: Yong, Melvin, и др.
Опубликовано: (2023)

Unveiling novel participants in the DNA damage response
по: Li, S
Опубликовано: (2024)

Telomere-related DNA damage response pathways in cancer therapy: prospective targets
по: Liting Gu, и др.
Опубликовано: (2024-06-01)

DNA damage and mutation. Types of DNA damage
по: Stoyan Chakarov, и др.
Опубликовано: (2014-02-01)

DNA damage checkpoint adaptation genes are required for division of cells harbouring eroded telomeres
по: Sofiane Y. Mersaoui, и др.
Опубликовано: (2015-09-01)

DNA Damage Response Pathways in Dinoflagellates
по: Chongping Li, и др.
Опубликовано: (2019-07-01)

Interactions between the DNA Damage Response and the Telomere Complex in Carcinogenesis: A Hypothesis
по: Antonio Torres-Montaner
Опубликовано: (2023-09-01)

Real-time studies of DNA repair kinetics following low-LET short-pulse electron radiation
по: Mendes de Oliveira Martins, CD
Опубликовано: (2014)

The DNA damage response in mammalian oocytes
по: John eCarroll, и др.
Опубликовано: (2013-06-01)

Development of bioreductive inhibitors of checkpoint kinase 1 to target hypoxic tumours
по: Körner, C
Опубликовано: (2015)

The role of DNA polymerase eta in determining cellular responses to chemo-radiation treatment
по: Nicolay, N
Опубликовано: (2013)

MiR-215 regulates differentiation in colorectal cancer stem cells
по: Jones, M
Опубликовано: (2014)

The role of LATS1 in DNA damage signalling
по: Latusek, R
Опубликовано: (2012)

Development of clinical biomarkers of DNA double strand breaks for cancer care
по: Shah, K
Опубликовано: (2012)

An analysis of the S. cerevisiae RMI1 gene
по: Ashton, TM
Опубликовано: (2010)

New research on DNA damage /
по: Kimura, Honoka, и др.
Опубликовано: (2008)

The chemical biology of DNA damage /
по: Geacintov, Nicholas E., 1935-, и др.
Опубликовано: (2010)

Structural basis of G-quadruplex DNA recognition by the yeast telomeric protein Rap1
по: Traczyk, Anna, и др.
Опубликовано: (2020)

The Role of MicroRNA in DNA Damage Response
по: Yongxin Li, и др.
Опубликовано: (2022-05-01)

Histone post-translational modification and the DNA damage response
по: Haoyun Song, и др.
Опубликовано: (2023-07-01)