Shape-based ultrasound tomography using a Born model with application to high intensity focused ultrasound therapy.

A shaped-based ultrasound tomography method is proposed to reconstruct ellipsoidal objects using a linearized scattering model. The method is motivated by the desire to detect the presence of lesions created by high intensity focused ultrasound (HIFU) in applications of cancer therapy. The computati...

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Main Authors: Ulker Karbeyaz, B, Miller, E, Cleveland, R
Format: Journal article
Language:English
Published: 2008
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author Ulker Karbeyaz, B
Miller, E
Cleveland, R
author_facet Ulker Karbeyaz, B
Miller, E
Cleveland, R
author_sort Ulker Karbeyaz, B
collection OXFORD
description A shaped-based ultrasound tomography method is proposed to reconstruct ellipsoidal objects using a linearized scattering model. The method is motivated by the desire to detect the presence of lesions created by high intensity focused ultrasound (HIFU) in applications of cancer therapy. The computational size and limited view nature of the relevant three-dimensional inverse problem renders impractical the use of traditional pixel-based reconstruction methods. However, by employing a shape-based parametrization it is only necessary to estimate a small number of unknowns describing the geometry of the lesion, in this paper assumed to be ellipsoidal. The details of the shape-based nonlinear inversion method are provided. Results obtained from a commercial ultrasound scanner and a tissue phantom containing a HIFU-like lesion demonstrate the feasibility of the approach where a 20 mm x 5 mm x 6 mm ellipsoidal inclusion was detected with an accuracy of around 5%.
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spelling oxford-uuid:27ddc396-038d-4c83-bd97-126318c70d142022-03-26T12:09:22ZShape-based ultrasound tomography using a Born model with application to high intensity focused ultrasound therapy.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:27ddc396-038d-4c83-bd97-126318c70d14EnglishSymplectic Elements at Oxford2008Ulker Karbeyaz, BMiller, ECleveland, RA shaped-based ultrasound tomography method is proposed to reconstruct ellipsoidal objects using a linearized scattering model. The method is motivated by the desire to detect the presence of lesions created by high intensity focused ultrasound (HIFU) in applications of cancer therapy. The computational size and limited view nature of the relevant three-dimensional inverse problem renders impractical the use of traditional pixel-based reconstruction methods. However, by employing a shape-based parametrization it is only necessary to estimate a small number of unknowns describing the geometry of the lesion, in this paper assumed to be ellipsoidal. The details of the shape-based nonlinear inversion method are provided. Results obtained from a commercial ultrasound scanner and a tissue phantom containing a HIFU-like lesion demonstrate the feasibility of the approach where a 20 mm x 5 mm x 6 mm ellipsoidal inclusion was detected with an accuracy of around 5%.
spellingShingle Ulker Karbeyaz, B
Miller, E
Cleveland, R
Shape-based ultrasound tomography using a Born model with application to high intensity focused ultrasound therapy.
title Shape-based ultrasound tomography using a Born model with application to high intensity focused ultrasound therapy.
title_full Shape-based ultrasound tomography using a Born model with application to high intensity focused ultrasound therapy.
title_fullStr Shape-based ultrasound tomography using a Born model with application to high intensity focused ultrasound therapy.
title_full_unstemmed Shape-based ultrasound tomography using a Born model with application to high intensity focused ultrasound therapy.
title_short Shape-based ultrasound tomography using a Born model with application to high intensity focused ultrasound therapy.
title_sort shape based ultrasound tomography using a born model with application to high intensity focused ultrasound therapy
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