High-density single nucleotide polymorphism array analysis and ASXL1 gene mutation screening in chronic myeloid leukemia during disease progression.

We have undertaken a genome-wide single nucleotide polymorphism (SNP) array analysis of 41 chronic myeloid leukemia (CML) patients. In total, 44 regions of uniparental disomy (UPD) >3 Mb were identified in 24 of 32 patients in chronic phase (CP), and 21 regions of UPD >3 Mb were identi...

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Bibliographic Details
Main Authors: Boultwood, J, Perry, J, Zaman, R, Fernandez-Santamaria, C, Littlewood, T, Kusec, R, Pellagatti, A, Wang, L, Clark, R, Wainscoat, J
Format: Journal article
Language:English
Published: 2010