Direct analysis of unphased SNP genotype data in population-based association studies via Bayesian partition modelling of haplotypes.
We describe a novel method for assessing the strength of disease association with single nucleotide polymorphisms (SNPs) in a candidate gene or small candidate region, and for estimating the corresponding haplotype relative risks of disease, using unphased genotype data directly. We begin by estimat...
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| Format: | Journal article |
| Language: | English |
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2005
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