Optogenetic silencing strategies differ in their effects on inhibitory synaptic transmission.

Optogenetic silencing using light-driven ion fluxes permits rapid and effective inhibition of neural activity. Using rodent hippocampal neurons, we found that silencing activity with a chloride pump can increase the probability of synaptically evoked spiking after photoactivation; this did not occur...

Descripción completa

Detalles Bibliográficos
Autores principales: Raimondo, J, Kay, L, Ellender, T, Akerman, C
Formato: Journal article
Lenguaje:English
Publicado: 2012