Physiological and pharmacological stimulation for in vitro maturation of substrate metabolism in human induced pluripotent stem cell-derived cardiomyocytes

Physiological and pharmacological stimulation for in vitro maturation of substrate metabolism in human induced pluripotent stem cell-derived cardiomyocytes

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) enable human cardiac cells to be studied in vitro, although they use glucose as their primary metabolic substrate and do not recapitulate the properties of adult cardiomyocytes. Here, we have explored the interplay between matura...

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Bibliographic Details
Main Authors: Lopez, C, Al Siddiqi, H, Purnama, U, Iftekhar, S, Bruyneel, A, Kerr, M, Nazir, R, Sousa Fialho, MDL, Malandraki-Miller, S, Alonaizan, R, Kermani, F, Heather, L, Czernuszka, J, Carr, C
Format: Journal article
Language:English
Published: Springer Nature 2021

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