Pharmacometric and electrocardiographic evaluation of chloroquine and azithromycin in healthy volunteers

Pharmacometric and electrocardiographic evaluation of chloroquine and azithromycin in healthy volunteers

Chloroquine and azithromycin were developed in combination for the preventive treatment of malaria in pregnancy, and more recently were proposed as coronavirus disease 2019 (COVID-19) treatment options. Billions of doses of chloroquine have been administered worldwide over the past 70 years but conc...

Полное описание

Библиографические подробности
Главные авторы:	Chotsiri, P, Tarning, J, Hoglund, RM, Watson, JA, White, NJ
Формат:	Journal article
Язык:	English
Опубликовано:	American Society for Clinical Pharmacology and Therapeutics 2022

Схожие документы

A pharmacometric approach to evaluate drugs for potential repurposing as COVID-19 therapeutics
по: Wattanakul, T, и др.
Опубликовано: (2022)

Population pharmacokinetics and electrocardiographic effects of dihydroartemisinin-piperaquine in healthy volunteers
по: Chotsiri, P, и др.
Опубликовано: (2017)

Concentration-dependent mortality of chloroquine in overdose
по: Watson, JA, и др.
Опубликовано: (2020)

COVID-19 prevention and treatment: A critical analysis of chloroquine and hydroxychloroquine clinical pharmacology
по: White, NJ, и др.
Опубликовано: (2020)

Primaquine in glucose-6-phosphate dehydrogenase deficiency: an adaptive pharmacometric assessment of ascending dose regimens in healthy volunteers
по: Pukrittayakamee, S, и др.
Опубликовано: (2024)

Mechanistic modeling of primaquine pharmacokinetics, gametocytocidal activity, and mosquito infectivity
по: Chotsiri, P, и др.
Опубликовано: (2022)

Pharmacokinetics of chloroquine and primaquine in healthy volunteers
по: André Daher, и др.
Опубликовано: (2022-01-01)

The status of pharmacometrics in pregnancy: highlights from the 3(rd) American conference on pharmacometrics.
по: van Hasselt, J, и др.
Опубликовано: (2012)

Primaquine in glucose-6-phosphate dehydrogenase deficiency: an adaptive pharmacometric assessment of ascending dose regimens in healthy volunteers
по: Sasithon Pukrittayakamee, и др.
Опубликовано: (2024-02-01)

Safety and pharmacokinetic properties of a new formulation of parenteral artesunate in healthy Thai volunteers
по: Tarning, J, и др.
Опубликовано: (2024)

Characterizing SARS-CoV-2 viral clearance kinetics to improve the design of antiviral pharmacometric studies
по: Watson, JA, и др.
Опубликовано: (2022)

An artesunate pharmacometric model to explain therapeutic responses in falciparum malaria.
по: Saralamba, S, и др.
Опубликовано: (2023)

Treatment of adults with acute uncomplicated malaria with azithromycin and chloroquine in India, Colombia, and Suriname
по: Kshirsagar NA, и др.
Опубликовано: (2017-10-01)

Pharmacokinetics And Pharmacodynamics Modeling Of Clozapine In Healthy Volunteers And Patients With Schizophrenia Spectrum Disorders Using Pharmacometrics Approach
по: Orwa, Albitar
Опубликовано: (2022)

Concentration-dependent mortality of chloroquine in overdose
по: James A Watson, и др.
Опубликовано: (2020-07-01)

Pharmacokinetic considerations in seasonal malaria chemoprevention
по: Chotsiri, P, и др.
Опубликовано: (2022)

Azithromycin-chloroquine and the intermittent preventive treatment of malaria in pregnancy
по: Greenwood Brian, и др.
Опубликовано: (2008-12-01)

Metaheuristics for pharmacometrics
по: Seongho Kim, и др.
Опубликовано: (2021-11-01)

COVID-19 prevention and treatment: A critical analysis of chloroquine and hydroxychloroquine clinical pharmacology.
по: Nicholas J White, и др.
Опубликовано: (2020-09-01)

CORRIGENDUM: Commentary on Pharmacometrics for Immunotherapy
по: MJ Garrido, и др.
Опубликовано: (2017-04-01)

Lysosomotropic agents including azithromycin, chloroquine and hydroxychloroquine activate the integrated stress response
по: Ai-Ling Tian, и др.
Опубликовано: (2021-01-01)

QTc Prolongation Risk Evaluation in Female COVID-19 Patients Undergoing Chloroquine and Hydroxychloroquine With/Without Azithromycin Treatment
по: Sarah Grewal, и др.
Опубликовано: (2020-09-01)

Safety and pharmacokinetic properties of a new formulation of parenteral artesunate in healthy Thai volunteers
по: Joel Tarning, и др.
Опубликовано: (2024-10-01)

Effect of antiretroviral therapy on plasma concentrations of chloroquine and desethyl-chloroquine
по: Ippolito, M, и др.
Опубликовано: (2018)

Killing of Staphylococcus aureus in murine macrophages by chloroquine used alone and in combination with ciprofloxacin or azithromycin
по: Dey S, и др.
Опубликовано: (2015-01-01)

Clinical and electrocardiographic outcomes evaluated by telemedicine of outpatients with clinical suspicion of COVID-19 treated with chloroquine compounds in Brazil†
по: Bruno R. Nascimento, и др.
Опубликовано: (2023-02-01)

Pharmacokinetic interactions between primaquine and chloroquine.
по: Pukrittayakamee, S, и др.
Опубликовано: (2014)

Welcome to the statistics and pharmacometrics themed issue
по: Jonathan French, и др.
Опубликовано: (2021-04-01)

Pharmacometrics of high dose ivermectin in early COVID-19: an open label, randomized, controlled adaptive platform trial (PLATCOV)
по: Schilling, WHK, и др.
Опубликовано: (2023)

Comparison of the umulative efficacy and safety of chloroquine, artesunate, and chloroquine-primaquine in Plasmodium vivax malaria
по: Chu, C, и др.
Опубликовано: (2018)

Comparison of the cumulative efficacy and safety of chloroquine, artesunate, and chloroquine-primaquine in plasmodium vivax malaria
по: Chu, C, и др.
Опубликовано: (2018)

Evaluation of machine learning methods for covariate data imputation in pharmacometrics
по: Dominic Stefan Bräm, и др.
Опубликовано: (2022-12-01)

Pharmacokinetics of high-dose oseltamivir in healthy volunteers.
по: Wattanagoon, Y, и др.
Опубликовано: (2009)

Covariate modeling in pharmacometrics: General points for consideration
по: Kinjal Sanghavi, и др.
Опубликовано: (2024-05-01)

A longitudinal trial comparing chloroquine as monotherapy or in combination with artesunate, azithromycin or atovaquone-proguanil to treat malaria.
по: Miriam K Laufer, и др.
Опубликовано: (2012-01-01)

A systematic review and meta-analysis on chloroquine and hydroxychloroquine as monotherapy or combined with azithromycin in COVID-19 treatment
по: Ramy Mohamed Ghazy, и др.
Опубликовано: (2020-12-01)

The Role of Pharmacometrics in Advancing the Therapies for Autoimmune Diseases
по: Artur Świerczek, и др.
Опубликовано: (2024-12-01)

Pharmacometrics approaches and its applications in diabetes: An overview
по: Sohail Aziz, и др.
Опубликовано: (2021-01-01)

Pharmacokinetics of artemether and dihydroartemisinin in healthy Pakistani male volunteers treated with artemether-lumefantrine.
по: Ali, S, и др.
Опубликовано: (2010)

Improving pharmacometrics analysis efficiency using DataCheQC: An interactive, Shiny‐based app for quality control of pharmacometrics datasets
по: Or Dotan, и др.
Опубликовано: (2023-10-01)