White matter and lesion T1 relaxation times increase in parallel and correlate with disability in multiple sclerosis.

Previous studies have established the clinical relevance of hypointense lesions ("black holes") on T1-weighted MRI as a surrogate marker for pathological change [36]. In contrast to measuring the volume of "black holes", the direct measurement of T1 values allows an objective ass...

Full description

Bibliographic Details
Main Authors: Parry, A, Clare, S, Jenkinson, M, Smith, S, Palace, J, Matthews, P
Format: Journal article
Language:English
Published: 2002