exTREEmaTIME: a method for incorporating uncertainty into divergence time estimates
We present a method of divergence time estimation (exTREEmaTIME) that aims to effectively account for uncertainty in divergence time estimates. The method requires a minimal set of assumptions, and, based on these assumptions, estimates the oldest possible divergence times and youngest possible dive...
Auteurs principaux: | , |
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Format: | Journal article |
Langue: | English |
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Company of Biologists
2022
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_version_ | 1826307522253815808 |
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author | Carruthers, T Scotland, RW |
author_facet | Carruthers, T Scotland, RW |
author_sort | Carruthers, T |
collection | OXFORD |
description | We present a method of divergence time estimation (exTREEmaTIME) that aims to effectively account for uncertainty in divergence time estimates. The method requires a minimal set of assumptions, and, based on these assumptions, estimates the oldest possible divergence times and youngest possible divergence times that are consistent with the assumptions. We use a series of simulations and empirical analyses to illustrate that exTREEmaTIME is effective at representing uncertainty. We then describe how exTREEmaTIME can act as a basis to determine the implications of the more stringent assumptions that are incorporated into other methods of divergence time estimation that produce more precise estimates. This is critically important given that many of the assumptions that are incorporated into these methods are highly complex, difficult to justify biologically, and as such can lead to estimates that are highly inaccurate. |
first_indexed | 2024-03-07T07:04:21Z |
format | Journal article |
id | oxford-uuid:280ac0b3-a524-442c-8f24-8112fa2fd2b8 |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-07T07:04:21Z |
publishDate | 2022 |
publisher | Company of Biologists |
record_format | dspace |
spelling | oxford-uuid:280ac0b3-a524-442c-8f24-8112fa2fd2b82022-04-27T11:48:16ZexTREEmaTIME: a method for incorporating uncertainty into divergence time estimatesJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:280ac0b3-a524-442c-8f24-8112fa2fd2b8EnglishSymplectic ElementsCompany of Biologists2022Carruthers, TScotland, RWWe present a method of divergence time estimation (exTREEmaTIME) that aims to effectively account for uncertainty in divergence time estimates. The method requires a minimal set of assumptions, and, based on these assumptions, estimates the oldest possible divergence times and youngest possible divergence times that are consistent with the assumptions. We use a series of simulations and empirical analyses to illustrate that exTREEmaTIME is effective at representing uncertainty. We then describe how exTREEmaTIME can act as a basis to determine the implications of the more stringent assumptions that are incorporated into other methods of divergence time estimation that produce more precise estimates. This is critically important given that many of the assumptions that are incorporated into these methods are highly complex, difficult to justify biologically, and as such can lead to estimates that are highly inaccurate. |
spellingShingle | Carruthers, T Scotland, RW exTREEmaTIME: a method for incorporating uncertainty into divergence time estimates |
title | exTREEmaTIME: a method for incorporating uncertainty into divergence time estimates |
title_full | exTREEmaTIME: a method for incorporating uncertainty into divergence time estimates |
title_fullStr | exTREEmaTIME: a method for incorporating uncertainty into divergence time estimates |
title_full_unstemmed | exTREEmaTIME: a method for incorporating uncertainty into divergence time estimates |
title_short | exTREEmaTIME: a method for incorporating uncertainty into divergence time estimates |
title_sort | extreematime a method for incorporating uncertainty into divergence time estimates |
work_keys_str_mv | AT carrutherst extreematimeamethodforincorporatinguncertaintyintodivergencetimeestimates AT scotlandrw extreematimeamethodforincorporatinguncertaintyintodivergencetimeestimates |