Characterising cancer cell responses to cyclic hypoxia using mathematical modelling

In vivo observations show that oxygen levels in tumours can fluctuate on fast and slow timescales. As a result, cancer cells can be periodically exposed to pathologically low oxygen levels; a phenomenon known as cyclic hypoxia. Yet, little is known about the response and adaptation of cancer cells t...

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Hlavní autoři: Celora, GL, Nixson, R, Pitt-Francis, J, Maini, P, Byrne, H
Médium: Journal article
Jazyk:English
Vydáno: Springer 2024