An Smc3 acetylation cycle is essential for establishment of sister chromatid cohesion.
Sister chromatid cohesion is thought to involve entrapment of sister DNAs by a tripartite ring composed of the cohesin subunits Smc1, Smc3, and Scc1. Establishment of cohesion during S phase depends on acetylation of Smc3's nucleotide-binding domain (NBD) by the Eco1 acetyl transferase. It is d...
Main Authors: | Beckouët, F, Hu, B, Roig, M, Sutani, T, Komata, M, Uluocak, P, Katis, V, Shirahige, K, Nasmyth, K |
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Format: | Journal article |
Language: | English |
Published: |
2010
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