Extending the human connectome project across ages: imaging protocols for the lifespan development and aging projects
The Human Connectome Projects in Development (HCP-D) and Aging (HCP-A) are two large-scale brain imaging studies that will extend the recently completed HCP Young-Adult (HCP-YA) project to nearly the full lifespan, collecting structural, resting-state fMRI, task-fMRI, diffusion, and perfusion MRI in...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
Elsevier
2018
|
| _version_ | 1797059421676765184 |
|---|---|
| author | Harms, MP Somerville, LH Ances, BM Andersson, J Barch, DM Bastiani, M Bookheimer, SY Brown, TB Buckner, RL Burgess, GC Coalson, TS Chappell, MA Dapretto, M Douaud, GLA Greve, DN Hodge, C Jamison, KW Jbabdi, S Kandala, S Li, X Mair, RW Mangia, S Marcus, D Mascali, D Moeller, S Nichols, TEP Robinson, EC Salat, DH Smith, SM Sotiropoulos, SN Terpstra, M Thomas, KM Tisdall, MD Ugurbil, K Van Der Kouwe, A Woods, RP Zöllei, L Van Essen, DC Yacoub, E |
| author_facet | Harms, MP Somerville, LH Ances, BM Andersson, J Barch, DM Bastiani, M Bookheimer, SY Brown, TB Buckner, RL Burgess, GC Coalson, TS Chappell, MA Dapretto, M Douaud, GLA Greve, DN Hodge, C Jamison, KW Jbabdi, S Kandala, S Li, X Mair, RW Mangia, S Marcus, D Mascali, D Moeller, S Nichols, TEP Robinson, EC Salat, DH Smith, SM Sotiropoulos, SN Terpstra, M Thomas, KM Tisdall, MD Ugurbil, K Van Der Kouwe, A Woods, RP Zöllei, L Van Essen, DC Yacoub, E |
| author_sort | Harms, MP |
| collection | OXFORD |
| description | The Human Connectome Projects in Development (HCP-D) and Aging (HCP-A) are two large-scale brain imaging studies that will extend the recently completed HCP Young-Adult (HCP-YA) project to nearly the full lifespan, collecting structural, resting-state fMRI, task-fMRI, diffusion, and perfusion MRI in participants from 5 to 100 + years of age. HCP-D is enrolling 1300 + healthy children, adolescents, and young adults (ages 5-21), and HCP-A is enrolling 1200 + healthy adults (ages 36-100+), with each study collecting longitudinal data in a subset of individuals at particular age ranges. The imaging protocols of the HCP-D and HCP-A studies are very similar, differing primarily in the selection of different task-fMRI paradigms. We strove to harmonize the imaging protocol to the greatest extent feasible with the completed HCP-YA (1200 + participants, aged 22-35), but some imaging-related changes were motivated or necessitated by hardware changes, the need to reduce the total amount of scanning per participant, and/or the additional challenges of working with young and elderly populations. Here, we provide an overview of the common HCP-D/A imaging protocol including data and rationales for protocol decisions and changes relative to HCP-YA. The result will be a large, rich, multi-modal, and freely available set of consistently acquired data for use by the scientific community to investigate and define normative developmental and aging related changes in the healthy human brain. |
| first_indexed | 2024-03-06T20:04:01Z |
| format | Journal article |
| id | oxford-uuid:284e55a6-7506-4535-a561-81fe55e4a6ba |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T20:04:01Z |
| publishDate | 2018 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oxford-uuid:284e55a6-7506-4535-a561-81fe55e4a6ba2022-03-26T12:12:11ZExtending the human connectome project across ages: imaging protocols for the lifespan development and aging projectsJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:284e55a6-7506-4535-a561-81fe55e4a6baEnglishSymplectic Elements at OxfordElsevier2018Harms, MPSomerville, LHAnces, BMAndersson, JBarch, DMBastiani, MBookheimer, SYBrown, TBBuckner, RLBurgess, GCCoalson, TSChappell, MADapretto, MDouaud, GLAGreve, DNHodge, CJamison, KWJbabdi, SKandala, SLi, XMair, RWMangia, SMarcus, DMascali, DMoeller, SNichols, TEPRobinson, ECSalat, DHSmith, SMSotiropoulos, SNTerpstra, MThomas, KMTisdall, MDUgurbil, KVan Der Kouwe, AWoods, RPZöllei, LVan Essen, DCYacoub, EThe Human Connectome Projects in Development (HCP-D) and Aging (HCP-A) are two large-scale brain imaging studies that will extend the recently completed HCP Young-Adult (HCP-YA) project to nearly the full lifespan, collecting structural, resting-state fMRI, task-fMRI, diffusion, and perfusion MRI in participants from 5 to 100 + years of age. HCP-D is enrolling 1300 + healthy children, adolescents, and young adults (ages 5-21), and HCP-A is enrolling 1200 + healthy adults (ages 36-100+), with each study collecting longitudinal data in a subset of individuals at particular age ranges. The imaging protocols of the HCP-D and HCP-A studies are very similar, differing primarily in the selection of different task-fMRI paradigms. We strove to harmonize the imaging protocol to the greatest extent feasible with the completed HCP-YA (1200 + participants, aged 22-35), but some imaging-related changes were motivated or necessitated by hardware changes, the need to reduce the total amount of scanning per participant, and/or the additional challenges of working with young and elderly populations. Here, we provide an overview of the common HCP-D/A imaging protocol including data and rationales for protocol decisions and changes relative to HCP-YA. The result will be a large, rich, multi-modal, and freely available set of consistently acquired data for use by the scientific community to investigate and define normative developmental and aging related changes in the healthy human brain. |
| spellingShingle | Harms, MP Somerville, LH Ances, BM Andersson, J Barch, DM Bastiani, M Bookheimer, SY Brown, TB Buckner, RL Burgess, GC Coalson, TS Chappell, MA Dapretto, M Douaud, GLA Greve, DN Hodge, C Jamison, KW Jbabdi, S Kandala, S Li, X Mair, RW Mangia, S Marcus, D Mascali, D Moeller, S Nichols, TEP Robinson, EC Salat, DH Smith, SM Sotiropoulos, SN Terpstra, M Thomas, KM Tisdall, MD Ugurbil, K Van Der Kouwe, A Woods, RP Zöllei, L Van Essen, DC Yacoub, E Extending the human connectome project across ages: imaging protocols for the lifespan development and aging projects |
| title | Extending the human connectome project across ages: imaging protocols for the lifespan development and aging projects |
| title_full | Extending the human connectome project across ages: imaging protocols for the lifespan development and aging projects |
| title_fullStr | Extending the human connectome project across ages: imaging protocols for the lifespan development and aging projects |
| title_full_unstemmed | Extending the human connectome project across ages: imaging protocols for the lifespan development and aging projects |
| title_short | Extending the human connectome project across ages: imaging protocols for the lifespan development and aging projects |
| title_sort | extending the human connectome project across ages imaging protocols for the lifespan development and aging projects |
| work_keys_str_mv | AT harmsmp extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT somervillelh extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT ancesbm extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT anderssonj extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT barchdm extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT bastianim extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT bookheimersy extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT browntb extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT bucknerrl extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT burgessgc extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT coalsonts extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT chappellma extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT daprettom extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT douaudgla extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT grevedn extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT hodgec extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT jamisonkw extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT jbabdis extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT kandalas extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT lix extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT mairrw extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT mangias extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT marcusd extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT mascalid extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT moellers extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT nicholstep extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT robinsonec extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT salatdh extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT smithsm extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT sotiropoulossn extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT terpstram extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT thomaskm extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT tisdallmd extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT ugurbilk extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT vanderkouwea extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT woodsrp extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT zolleil extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT vanessendc extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects AT yacoube extendingthehumanconnectomeprojectacrossagesimagingprotocolsforthelifespandevelopmentandagingprojects |