US exceptionalism? International trends in midlife mortality

<p><strong>Background:&nbsp;</strong>Rising midlife mortality in the USA has raised concerns, particularly the increase in &lsquo;deaths of despair&rsquo; (due to drugs, alcohol and suicide). Life expectancy is also stalling in other countries such as the UK, but how tr...

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Main Authors: Dowd, JB, Doniec, K, Zhang, L, Tilstra, A
Format: Journal article
Language:English
Published: Oxford University Press 2024
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author Dowd, JB
Doniec, K
Zhang, L
Tilstra, A
author_facet Dowd, JB
Doniec, K
Zhang, L
Tilstra, A
author_sort Dowd, JB
collection OXFORD
description <p><strong>Background:&nbsp;</strong>Rising midlife mortality in the USA has raised concerns, particularly the increase in &lsquo;deaths of despair&rsquo; (due to drugs, alcohol and suicide). Life expectancy is also stalling in other countries such as the UK, but how trends in midlife mortality are evolving outside the USA is less understood. We provide a synthesis of cause-specific mortality trends in midlife (25&ndash;64&nbsp;years of age) for the USA and the UK as well as other high-income and Central and Eastern European (CEE) countries.</p> <p><strong>Methods:&nbsp;</strong>We document trends in midlife mortality in the USA, UK and a group of 13 high-income countries in Western Europe, Australia, Canada and Japan, as well as seven CEE countries from 1990 to 2019. We use annual mortality data from the World Health Organization Mortality Database to analyse sex- and age-specific (25&ndash;44, 45&ndash;54 and 55&ndash;64&nbsp;years) age-standardized death rates across 15 major cause-of-death categories.</p> <p><strong>Results:&nbsp;</strong>US midlife mortality rates have worsened since 1990 for several causes of death including drug-related, alcohol-related, suicide, metabolic diseases, nervous system diseases, respiratory diseases and infectious/parasitic diseases. Deaths due to homicide, transport accidents and cardiovascular diseases have declined since 1990 but saw recent increases or stalling of improvements. Midlife mortality also increased in the UK for people aged 45&ndash;54&nbsp;year and in Canada, Poland and Sweden among for those aged 25&ndash;44 years.</p> <p><strong>Conclusions:&nbsp;</strong>The USA is increasingly falling behind not only high-income, but also CEE countries, some of which were heavily impacted by the post-socialist mortality crisis of the 1990s. Although levels of midlife mortality in the UK are substantially lower than those in the USA overall, there are signs that UK midlife mortality is worsening relative to that in Western Europe.</p>
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spelling oxford-uuid:285c9bdd-26e1-471b-9dad-c9ab8707b4632024-12-11T15:53:37ZUS exceptionalism? International trends in midlife mortalityJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:285c9bdd-26e1-471b-9dad-c9ab8707b463EnglishSymplectic ElementsOxford University Press2024Dowd, JBDoniec, KZhang, LTilstra, A<p><strong>Background:&nbsp;</strong>Rising midlife mortality in the USA has raised concerns, particularly the increase in &lsquo;deaths of despair&rsquo; (due to drugs, alcohol and suicide). Life expectancy is also stalling in other countries such as the UK, but how trends in midlife mortality are evolving outside the USA is less understood. We provide a synthesis of cause-specific mortality trends in midlife (25&ndash;64&nbsp;years of age) for the USA and the UK as well as other high-income and Central and Eastern European (CEE) countries.</p> <p><strong>Methods:&nbsp;</strong>We document trends in midlife mortality in the USA, UK and a group of 13 high-income countries in Western Europe, Australia, Canada and Japan, as well as seven CEE countries from 1990 to 2019. We use annual mortality data from the World Health Organization Mortality Database to analyse sex- and age-specific (25&ndash;44, 45&ndash;54 and 55&ndash;64&nbsp;years) age-standardized death rates across 15 major cause-of-death categories.</p> <p><strong>Results:&nbsp;</strong>US midlife mortality rates have worsened since 1990 for several causes of death including drug-related, alcohol-related, suicide, metabolic diseases, nervous system diseases, respiratory diseases and infectious/parasitic diseases. Deaths due to homicide, transport accidents and cardiovascular diseases have declined since 1990 but saw recent increases or stalling of improvements. Midlife mortality also increased in the UK for people aged 45&ndash;54&nbsp;year and in Canada, Poland and Sweden among for those aged 25&ndash;44 years.</p> <p><strong>Conclusions:&nbsp;</strong>The USA is increasingly falling behind not only high-income, but also CEE countries, some of which were heavily impacted by the post-socialist mortality crisis of the 1990s. Although levels of midlife mortality in the UK are substantially lower than those in the USA overall, there are signs that UK midlife mortality is worsening relative to that in Western Europe.</p>
spellingShingle Dowd, JB
Doniec, K
Zhang, L
Tilstra, A
US exceptionalism? International trends in midlife mortality
title US exceptionalism? International trends in midlife mortality
title_full US exceptionalism? International trends in midlife mortality
title_fullStr US exceptionalism? International trends in midlife mortality
title_full_unstemmed US exceptionalism? International trends in midlife mortality
title_short US exceptionalism? International trends in midlife mortality
title_sort us exceptionalism international trends in midlife mortality
work_keys_str_mv AT dowdjb usexceptionalisminternationaltrendsinmidlifemortality
AT donieck usexceptionalisminternationaltrendsinmidlifemortality
AT zhangl usexceptionalisminternationaltrendsinmidlifemortality
AT tilstraa usexceptionalisminternationaltrendsinmidlifemortality