RNA polymerase pausing during initial transcription

In bacteria, RNA polymerase (RNAP) initiates transcription by synthesizing short transcripts that are either released or extended to allow RNAP to escape from the promoter. The mechanism of initial transcription is unclear due to the presence of transient intermediates and molecular heterogeneity. H...

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Hlavní autoři: Duchi, D, Bauer, D, Fernandez, L, Evans, G, Robb, N, Hwang, L, Gryte, K, Tomescu, A, Zawadzki, P, Morichaud, Z, Brodolin, K, Kapanidis, A
Médium: Journal article
Jazyk:English
Vydáno: Cell Press 2016