RNA polymerase pausing during initial transcription

RNA polymerase pausing during initial transcription

In bacteria, RNA polymerase (RNAP) initiates transcription by synthesizing short transcripts that are either released or extended to allow RNAP to escape from the promoter. The mechanism of initial transcription is unclear due to the presence of transient intermediates and molecular heterogeneity. H...

Bibliografske podrobnosti
Main Authors:	Duchi, D, Bauer, D, Fernandez, L, Evans, G, Robb, N, Hwang, L, Gryte, K, Tomescu, A, Zawadzki, P, Morichaud, Z, Brodolin, K, Kapanidis, A
Format:	Journal article
Jezik:	English
Izdano:	Cell Press 2016

Podobne knjige/članki

Conformational heterogeneity and bubble dynamics in single bacterial transcription initiation complexes
od: Duchi, D, et al.
Izdano: (2017)

Pausing controls branching between productive and non-productive pathways during initial transcription in bacteria
od: Dulin, D, et al.
Izdano: (2018)

The transcription bubble of the RNA polymerase-promoter open complex exhibits conformational heterogeneity and millisecond-scale dynamics: Implications for transcription start-site selection
od: Robb, N, et al.
Izdano: (2013)

The transcription bubble of the RNA polymerase-promoter open complex exhibits conformational heterogeneity and millisecond-scale dynamics: implications for transcription start-site selection.
od: Robb, N, et al.
Izdano: (2013)

Pausing controls branching between productive and non-productive pathways during initial transcription in bacteria
od: David Dulin, et al.
Izdano: (2018-04-01)

Single-Molecule Studies of Transcription Initiation using a Vesicle Approach
od: Llumigusin, D, et al.
Izdano: (2012)

CDK9-dependent RNA polymerase II pausing controls transcription initiation
od: Saskia Gressel, et al.
Izdano: (2017-10-01)

Real-time transcription initiation by E. coli RNA polymerase in vitro and in vivo
od: Plochowietz, A, et al.
Izdano: (2015)

RNA polymerase II pausing in development: orchestrating transcription
od: Abderhman Abuhashem, et al.
Izdano: (2022-01-01)

Sensing DNA opening in transcription using quenchable Forster resonance energy transfer.
od: Cordes, T, et al.
Izdano: (2010)

A pause site for RNA polymerase II is associated with termination of transcription.
od: Enriquez-Harris, P, et al.
Izdano: (1991)

Role of R-loops in pause-dependent transcriptional termination of RNA polymerase II
od: Skourti-Stathaki, K
Izdano: (2012)

Pause sequences facilitate entry into long-lived paused states by reducing RNA polymerase transcription rates
od: Ronen Gabizon, et al.
Izdano: (2018-07-01)

Pause sites promote transcriptional termination of mammalian RNA polymerase II.
od: Gromak, N, et al.
Izdano: (2006)

Role of RNA Polymerase II Promoter-Proximal Pausing in Viral Transcription
od: Marilyn Whelan, et al.
Izdano: (2022-09-01)

Characterizing Influenza a RNA Polymerase - Promoter Interaction using Ensemble Fluorescence Spectroscopy
od: Tomescu, A, et al.
Izdano: (2013)

Single-molecule FRET reveals a corkscrew RNA structure for the polymerase-bound influenza virus promoter.
od: Tomescu, A, et al.
Izdano: (2014)

Initial transcription by RNA polymerase proceeds through a DNA-scrunching mechanism.
od: Kapanidis, A, et al.
Izdano: (2006)

Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization
od: Zakia Morichaud, et al.
Izdano: (2023-01-01)

Single-molecule studies of transcription initiation
od: Duchi Llumigusin, D, et al.
Izdano: (2014)

The RNA polymerase clamp interconverts dynamically among three states and is stabilized in a partly closed state by ppGpp
od: Duchi, D, et al.
Izdano: (2018)

A Role for FACT in RNA Polymerase II Promoter-Proximal Pausing
od: Theophilus T. Tettey, et al.
Izdano: (2019-06-01)

A-MYB and BRDT-dependent RNA Polymerase II pause release orchestrates transcriptional regulation in mammalian meiosis
od: Adriana K. Alexander, et al.
Izdano: (2023-03-01)

The pause-initiation limit restricts transcription activation in human cells
od: Saskia Gressel, et al.
Izdano: (2019-08-01)

Reporter-ChIP-nexus reveals strong contribution of the Drosophila initiator sequence to RNA polymerase pausing
od: Wanqing Shao, et al.
Izdano: (2019-04-01)

The elemental mechanism of transcriptional pausing
od: Jason Saba, et al.
Izdano: (2019-01-01)

Poly(A) signals and transcriptional pause sites combine to prevent interference between RNA polymerase II promoters.
od: Eggermont, J, et al.
Izdano: (1993)

RNA polymerase II pausing downstream of core histone genes is different from genes producing polyadenylated transcripts.
od: Krishanpal Anamika, et al.
Izdano: (2012-01-01)

Improved temporal resolution and linked hidden Markov modeling for switchable single-molecule FRET.
od: Uphoff, S, et al.
Izdano: (2011)

Transcription Pause and Escape in Neurodevelopmental Disorders
od: Kristel N. Eigenhuis, et al.
Izdano: (2022-05-01)

Tyrosine 1-phosphorylated RNA polymerase II transcribes PROMPTs to facilitate proximal promoter pausing and induce global transcriptional repression in response to DNA damage
od: Ajit, K, et al.
Izdano: (2024)

New core promoter element in RNA polymerase II-dependent transcription: sequence-specific DNA binding by transcription factor IIB.
od: Lagrange, T, et al.
Izdano: (1998)

Transcriptional regulation: effects of promoter proximal pausing on speed, synchrony and reliability.
od: Alistair N Boettiger, et al.
Izdano: (2011-05-01)

RNA Polymerase II pausing temporally coordinates cell cycle progression and erythroid differentiation
od: Martell, DJ, et al.
Izdano: (2023)

RNA polymerase II pausing temporally coordinates cell cycle progression and erythroid differentiation.
od: Martell, DJ, et al.
Izdano: (2023)

Grounded: Transcriptional Pausing in Naive mESCs
od: Guenther, Matthew G., et al.
Izdano: (2014)

YEAST RNA POLYMERASE-II TRANSCRIPTION - ENZYMATIC-ACTIVITIES OF GENERAL INITIATION-FACTORS, 3-D STRUCTURES OF INITIATION-FACTORS AND RNA-POLYMERASE, AND MECHANISM OF TRANSCRIPTIONAL ACTIVATION
od: Kornberg, R, et al.
Izdano: (1992)

Structures of co-transcriptional RNA capping enzymes on paused transcription complex
od: Yan Li, et al.
Izdano: (2024-05-01)

Definition of transcriptional pause elements in fission yeast.
od: Aranda, A, et al.
Izdano: (1999)

c-Myc regulates transcriptional pause release
od: Rahl, Peter B., et al.
Izdano: (2012)