Synthesis and structure–activity relationship of dehydrodieugenol B neolignans against Trypanosoma cruzi

Trypanosoma cruzi is the etiologic agent of Chagas disease, which affects over seven million people, especially in developing countries. Undesirable side effects are frequently associated with current therapies, which are typically ineffective in the treatment of all stages of the disease. Here, we...

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Detalhes bibliográficos
Principais autores: Sear, CE, Pieper, P, Amaral, M, Romanelli, MM, Costa-Silva, TA, Haugland, MM, Tate, JA, Lago, JHG, Tempone, AG, Anderson, EA
Formato: Journal article
Idioma:English
Publicado em: American Chemical Society 2020