T cell progenitor therapy–facilitated thymopoiesis depends upon thymic input and continued thymic microenvironment interaction

T cell progenitor therapy–facilitated thymopoiesis depends upon thymic input and continued thymic microenvironment interaction

Infusion of in vitro–derived T cell progenitor (proT) therapy with hematopoietic stem cell transplant aids the recovery of the thymus damaged by total body irradiation. To understand the interaction between proTs and the thymic microenvironment, WT mice were lethally irradiated and given T cell–defi...

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Detalles Bibliográficos
Autores principales: Smith, M, Reichenbach, D, Parker, S, Riddle, M, Mitchell, J, Osum, K, Mohtashami, M, Stefanski, H, Fife, B, Bhandoola, A, Hogquist, K, Holländer, G, Zúñiga-Pflücker, J, Tolar, J, Blazar, B
Formato: Journal article
Publicado: American Society for Clinical Investigatio 2017

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