Conformational heterogeneity and bubble dynamics in single bacterial transcription initiation complexes

Conformational heterogeneity and bubble dynamics in single bacterial transcription initiation complexes

Transcription initiation is a major step in gene regulation for all organisms. In bacteria, the promoter DNA is first recognized by RNA polymerase (RNAP) to yield an initial closed complex. This complex subsequently undergoes conformational changes resulting in DNA strand separation to form a transc...

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Main Authors:	Duchi, D, Gryte, K, Robb, N, Morichaud, Z, Sheppard, C, Brodolin, K, Wigneshweraraj, S, Kapanidis, A
格式:	Journal article
出版:	Oxford University Press 2017

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