Conformational heterogeneity and bubble dynamics in single bacterial transcription initiation complexes
Transcription initiation is a major step in gene regulation for all organisms. In bacteria, the promoter DNA is first recognized by RNA polymerase (RNAP) to yield an initial closed complex. This complex subsequently undergoes conformational changes resulting in DNA strand separation to form a transc...
| Hlavní autoři: | , , , , , , , |
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| Médium: | Journal article |
| Vydáno: |
Oxford University Press
2017
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