Aspects of native proteins are retained in vacuum.
It is now well established that protein complexes can be maintained in the gas phase, under the reduced pressure conditions experienced within mass spectrometers. This remains an intriguing phenomenon, given the importance placed on water molecules in stabilizing protein structure. As a consequence,...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2006
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| _version_ | 1826264343824564224 |
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| author | Ruotolo, B Robinson, C |
| author_facet | Ruotolo, B Robinson, C |
| author_sort | Ruotolo, B |
| collection | OXFORD |
| description | It is now well established that protein complexes can be maintained in the gas phase, under the reduced pressure conditions experienced within mass spectrometers. This remains an intriguing phenomenon, given the importance placed on water molecules in stabilizing protein structure. As a consequence, the overall structure of protein molecules and their complexes in the gas phase continues to stimulate much research. The eventual outcomes of this research will not only increase the number of applications of mass spectrometry to structural biology, but will also enhance our understanding of the interactions important for maintaining protein complexes in the absence of bulk solvent. |
| first_indexed | 2024-03-06T20:06:17Z |
| format | Journal article |
| id | oxford-uuid:29027bf5-ef35-4995-9515-12de48f348c3 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T20:06:17Z |
| publishDate | 2006 |
| record_format | dspace |
| spelling | oxford-uuid:29027bf5-ef35-4995-9515-12de48f348c32022-03-26T12:16:32ZAspects of native proteins are retained in vacuum.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:29027bf5-ef35-4995-9515-12de48f348c3EnglishSymplectic Elements at Oxford2006Ruotolo, BRobinson, CIt is now well established that protein complexes can be maintained in the gas phase, under the reduced pressure conditions experienced within mass spectrometers. This remains an intriguing phenomenon, given the importance placed on water molecules in stabilizing protein structure. As a consequence, the overall structure of protein molecules and their complexes in the gas phase continues to stimulate much research. The eventual outcomes of this research will not only increase the number of applications of mass spectrometry to structural biology, but will also enhance our understanding of the interactions important for maintaining protein complexes in the absence of bulk solvent. |
| spellingShingle | Ruotolo, B Robinson, C Aspects of native proteins are retained in vacuum. |
| title | Aspects of native proteins are retained in vacuum. |
| title_full | Aspects of native proteins are retained in vacuum. |
| title_fullStr | Aspects of native proteins are retained in vacuum. |
| title_full_unstemmed | Aspects of native proteins are retained in vacuum. |
| title_short | Aspects of native proteins are retained in vacuum. |
| title_sort | aspects of native proteins are retained in vacuum |
| work_keys_str_mv | AT ruotolob aspectsofnativeproteinsareretainedinvacuum AT robinsonc aspectsofnativeproteinsareretainedinvacuum |