Preparation of methyl (1R,2S,5S)- and (1S,2R,5R)-2-amino-5-tert-butyl-cyclopentane-1-carboxylates by parallel kinetic resolution of methyl (RS)-5-tert-butyl-cyclopentene-1-carboxylate.

Comparison of the kinetic and parallel kinetic resolutions of methyl (RS)-5-tert-butyl-cyclopentene-1-carboxylate allows for the efficient synthesis of both (1R,2S,5S)- and (1S,2R,5R)-enantiomers of methyl 2-amino-5-tert-butyl-cyclopentane-1-carboxylate.

Manylion Llyfryddiaeth
Prif Awduron: Davies, S, Díez, D, Hammouni, E, Garner, A, Garrido, N, Long, M, Morrison, R, Smith, A, Sweet, M, Withey, J
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2003