Prospects of future typhoid and paratyphoid vaccines in endemic countries
Low- and middle-income countries face a high burden of typhoid and paratyphoid fever due to poor water quality and inadequate sanitation. The World Health Organization (WHO) recommends the use of typhoid conjugate vaccines (TCV) in endemic settings and Gavi, the Vaccine Alliance, supports TCV introd...
| Główni autorzy: | , , |
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| Format: | Journal article |
| Język: | English |
| Wydane: |
Infectious Diseases Society of America
2021
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| _version_ | 1826264354049228800 |
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| author | Shakya, M Neuzil, KM Pollard, AJ |
| author_facet | Shakya, M Neuzil, KM Pollard, AJ |
| author_sort | Shakya, M |
| collection | OXFORD |
| description | Low- and middle-income countries face a high burden of typhoid and paratyphoid fever due to poor water quality and inadequate sanitation. The World Health Organization (WHO) recommends the use of typhoid conjugate vaccines (TCV) in endemic settings and Gavi, the Vaccine Alliance, supports TCV introduction. There are currently 2 WHO-prequalified TCVs with Typbar TCV introduced in Pakistan, Liberia, and Zimbabwe. Countries should assess disease burden and consider introduction of TCV for programmatic use. Several paratyphoid vaccine candidates are in early stages of development. An effective bivalent vaccine would be the most efficient way to control typhoid and paratyphoid fever. |
| first_indexed | 2024-03-06T20:06:27Z |
| format | Journal article |
| id | oxford-uuid:290fd7f2-c53c-49dc-acaa-d5381cd4645d |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T20:06:27Z |
| publishDate | 2021 |
| publisher | Infectious Diseases Society of America |
| record_format | dspace |
| spelling | oxford-uuid:290fd7f2-c53c-49dc-acaa-d5381cd4645d2022-03-26T12:16:46ZProspects of future typhoid and paratyphoid vaccines in endemic countriesJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:290fd7f2-c53c-49dc-acaa-d5381cd4645dEnglishSymplectic ElementsInfectious Diseases Society of America2021Shakya, MNeuzil, KMPollard, AJLow- and middle-income countries face a high burden of typhoid and paratyphoid fever due to poor water quality and inadequate sanitation. The World Health Organization (WHO) recommends the use of typhoid conjugate vaccines (TCV) in endemic settings and Gavi, the Vaccine Alliance, supports TCV introduction. There are currently 2 WHO-prequalified TCVs with Typbar TCV introduced in Pakistan, Liberia, and Zimbabwe. Countries should assess disease burden and consider introduction of TCV for programmatic use. Several paratyphoid vaccine candidates are in early stages of development. An effective bivalent vaccine would be the most efficient way to control typhoid and paratyphoid fever. |
| spellingShingle | Shakya, M Neuzil, KM Pollard, AJ Prospects of future typhoid and paratyphoid vaccines in endemic countries |
| title | Prospects of future typhoid and paratyphoid vaccines in endemic countries |
| title_full | Prospects of future typhoid and paratyphoid vaccines in endemic countries |
| title_fullStr | Prospects of future typhoid and paratyphoid vaccines in endemic countries |
| title_full_unstemmed | Prospects of future typhoid and paratyphoid vaccines in endemic countries |
| title_short | Prospects of future typhoid and paratyphoid vaccines in endemic countries |
| title_sort | prospects of future typhoid and paratyphoid vaccines in endemic countries |
| work_keys_str_mv | AT shakyam prospectsoffuturetyphoidandparatyphoidvaccinesinendemiccountries AT neuzilkm prospectsoffuturetyphoidandparatyphoidvaccinesinendemiccountries AT pollardaj prospectsoffuturetyphoidandparatyphoidvaccinesinendemiccountries |