Sialic acid in the lipopolysaccharide of Haemophilus influenzae: strain distribution, influence on serum resistance and structural characterization.

A survey of Haemophilus influenzae strains indicated that around one-third of capsular strains and over two-thirds of non-typeable strains included sialic acid in their lipopolysaccharides (LPS). Mutation of the CMP-Neu5Ac synthetase gene (siaB) resulted in a sialylation-deficient phenotype. Isogeni...

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Autori principali: Hood, D, Makepeace, K, Deadman, M, Rest, R, Thibault, P, Martin, A, Richards, J, Moxon, E
Natura: Journal article
Lingua:English
Pubblicazione: 1999