In vitro functional effects of XPC gene rare variants from bladder cancer patients.

In vitro functional effects of XPC gene rare variants from bladder cancer patients.

The XPC gene is involved in repair of bulky DNA adducts formed by carcinogenic metabolites and oxidative DNA damage, both known bladder cancer risk factors. Single nucleotide polymorphisms (SNPs) in XPC have been associated with increased bladder cancer risk. Recently, rarer genetic variants have be...

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Détails bibliographiques
Auteurs principaux:	Qiao, B, Ansari, A, Scott, G, Sak, S, Chambers, P, Elliott, F, Teo, M, Bentley, J, Churchman, M, Hall, J, Taylor, C, Bishop, T, Knowles, M, Kiltie, A
Format:	Journal article
Langue:	English
Publié:	2011

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