In vitro functional effects of XPC gene rare variants from bladder cancer patients.

The XPC gene is involved in repair of bulky DNA adducts formed by carcinogenic metabolites and oxidative DNA damage, both known bladder cancer risk factors. Single nucleotide polymorphisms (SNPs) in XPC have been associated with increased bladder cancer risk. Recently, rarer genetic variants have be...

詳細記述

書誌詳細
主要な著者: Qiao, B, Ansari, A, Scott, G, Sak, S, Chambers, P, Elliott, F, Teo, M, Bentley, J, Churchman, M, Hall, J, Taylor, C, Bishop, T, Knowles, M, Kiltie, A
フォーマット: Journal article
言語:English
出版事項: 2011