Polymorphism of the 5-HT transporter and response to antidepressants: randomised controlled trial.

BACKGROUND: Antidepressants exhibit a variety of pharmacological actions including inhibition of the serotonin and noradrenaline transporters. We wished to investigate whether genetic variation could be used to target or personalise treatment, in a comparison of selective serotonin reuptake inhibito...

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Main Authors: Lewis, G, Mulligan, J, Wiles, N, Cowen, P, Craddock, N, Ikeda, M, Grozeva, D, Mason, V, Nutt, D, Sharp, D, Tallon, D, Thomas, L, O'Donovan, M, Peters, T
格式: Journal article
语言:English
出版: 2011