Specific interaction between genotype, smoking and autoimmunity to citrullinated alpha-enolase in the etiology of rheumatoid arthritis.

Gene-environment associations are important in rheumatoid arthritis (RA) susceptibility, with an association existing between smoking, HLA- DRB1 'shared epitope' alleles, PTPN22 and antibodies to cyclic citrullinated peptides (CCP). Here, we test the hypothesis that a subset of the anti-CC...

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Bibliographic Details
Main Authors:	Mahdi, H, Fisher, B, Källberg, H, Plant, D, Malmström, V, Rönnelid, J, Charles, P, Ding, B, Alfredsson, L, Padyukov, L, Symmons, D, Venables, P, Klareskog, L, Lundberg, K
Format:	Journal article
Language:	English
Published:	2009

Specific interaction between genotype, smoking and autoimmunity to citrullinated alpha-enolase in the etiology of rheumatoid arthritis.

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