Structural basis for complement factor H linked age-related macular degeneration.
Nearly 50 million people worldwide suffer from age-related macular degeneration (AMD), which causes severe loss of central vision. A single-nucleotide polymorphism in the gene for the complement regulator factor H (FH), which causes a Tyr-to-His substitution at position 402, is linked to approximate...
Main Authors: | Prosser, B, Johnson, S, Roversi, P, Herbert, A, Blaum, B, Tyrrell, J, Jowitt, T, Clark, S, Tarelli, E, Uhrín, D, Barlow, P, Sim, R, Day, A, Lea, S |
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Format: | Journal article |
Language: | English |
Published: |
2007
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