Dynamics and constraints of early infant diagnosis of HIV infection in Rural Kenya.

A cohort design was used to determine uptake and drop out of 213 HIV-exposed infants eligible for Early Infant Diagnosis (EID) of HIV. To explore service providers and care givers knowledge, attitudes and perceptions of the EID process, observations and in-depth interviews were conducted. 145 (68%)...

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Main Authors: Hassan, A, Sakwa, E, Nabwera, H, Taegtmeyer, M, Kimutai, R, Sanders, E, Awuondo, K, Mutinda, M, Molyneux, C, Berkley, J
Format: Journal article
Language:English
Published: 2012
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author Hassan, A
Sakwa, E
Nabwera, H
Taegtmeyer, M
Kimutai, R
Sanders, E
Awuondo, K
Mutinda, M
Molyneux, C
Berkley, J
author_facet Hassan, A
Sakwa, E
Nabwera, H
Taegtmeyer, M
Kimutai, R
Sanders, E
Awuondo, K
Mutinda, M
Molyneux, C
Berkley, J
author_sort Hassan, A
collection OXFORD
description A cohort design was used to determine uptake and drop out of 213 HIV-exposed infants eligible for Early Infant Diagnosis (EID) of HIV. To explore service providers and care givers knowledge, attitudes and perceptions of the EID process, observations and in-depth interviews were conducted. 145 (68%) infants enrolled after 2 months of age. 139 (65%) dropped out before follow up to 18 months old. 60 (43%) drop outs occurred within 2 months of enrolment. Maternal factors associated with infant drop out were maternal loss to follow up (48 [68%] vs. 8 [20%], P < 0.001) and younger maternal age (27.2 vs. 30.1 years, P = 0.033). Service providers and caregivers had inadequate training, knowledge and understanding of EID. Poverty and lack of social support were challenges in accessing EID services. EID should be more closely aligned within PMTCT services, integrated with routine mother and child health (MCH) activities and its implementation more closely monitored.
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spelling oxford-uuid:298bcd31-2e84-4390-9c9f-7ab1a93263972022-03-26T12:19:50ZDynamics and constraints of early infant diagnosis of HIV infection in Rural Kenya.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:298bcd31-2e84-4390-9c9f-7ab1a9326397EnglishSymplectic Elements at Oxford2012Hassan, ASakwa, ENabwera, HTaegtmeyer, MKimutai, RSanders, EAwuondo, KMutinda, MMolyneux, CBerkley, JA cohort design was used to determine uptake and drop out of 213 HIV-exposed infants eligible for Early Infant Diagnosis (EID) of HIV. To explore service providers and care givers knowledge, attitudes and perceptions of the EID process, observations and in-depth interviews were conducted. 145 (68%) infants enrolled after 2 months of age. 139 (65%) dropped out before follow up to 18 months old. 60 (43%) drop outs occurred within 2 months of enrolment. Maternal factors associated with infant drop out were maternal loss to follow up (48 [68%] vs. 8 [20%], P < 0.001) and younger maternal age (27.2 vs. 30.1 years, P = 0.033). Service providers and caregivers had inadequate training, knowledge and understanding of EID. Poverty and lack of social support were challenges in accessing EID services. EID should be more closely aligned within PMTCT services, integrated with routine mother and child health (MCH) activities and its implementation more closely monitored.
spellingShingle Hassan, A
Sakwa, E
Nabwera, H
Taegtmeyer, M
Kimutai, R
Sanders, E
Awuondo, K
Mutinda, M
Molyneux, C
Berkley, J
Dynamics and constraints of early infant diagnosis of HIV infection in Rural Kenya.
title Dynamics and constraints of early infant diagnosis of HIV infection in Rural Kenya.
title_full Dynamics and constraints of early infant diagnosis of HIV infection in Rural Kenya.
title_fullStr Dynamics and constraints of early infant diagnosis of HIV infection in Rural Kenya.
title_full_unstemmed Dynamics and constraints of early infant diagnosis of HIV infection in Rural Kenya.
title_short Dynamics and constraints of early infant diagnosis of HIV infection in Rural Kenya.
title_sort dynamics and constraints of early infant diagnosis of hiv infection in rural kenya
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