Asymmetric syntheses of the 1-hydroxymethyl-2-hydroxy substituted pyrrolizidines (−)-macronecine, (−)-petasinecine, (−)-1-epi-macronecine, (+)-1-epi-petasinecine and (+)-2-epi-rosmarinecine
The asymmetric syntheses of all four possible diastereoisomeric 1-hydroxymethyl-2-hydroxy substituted pyrrolizidines, (−)-macronecine, (−)-petasinecine, (−)-1-epi-macronecine and (+)-1-epi-petasinecine, are reported. Conjugate addition of lithium (S)-N-benzyl-N-(α-methylbenzyl)amide to tert-butyl (E...
المؤلفون الرئيسيون: | Brambilla, M, Davies, S, Fletcher, A, Roberts, P, Thomson, J |
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التنسيق: | Journal article |
منشور في: |
Elsevier
2016
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مواد مشابهة
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Asymmetric and enantiospecific syntheses of 1-hydroxymethyl pyrrolizidine alkaloids
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