Asymmetric syntheses of the 1-hydroxymethyl-2-hydroxy substituted pyrrolizidines (−)-macronecine, (−)-petasinecine, (−)-1-epi-macronecine, (+)-1-epi-petasinecine and (+)-2-epi-rosmarinecine
The asymmetric syntheses of all four possible diastereoisomeric 1-hydroxymethyl-2-hydroxy substituted pyrrolizidines, (−)-macronecine, (−)-petasinecine, (−)-1-epi-macronecine and (+)-1-epi-petasinecine, are reported. Conjugate addition of lithium (S)-N-benzyl-N-(α-methylbenzyl)amide to tert-butyl (E...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Izdano: |
Elsevier
2016
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