Imaging of translocator protein upregulation is selective for pro‐inflammatory polarized astrocytes and microglia
<p>Translocator protein (TSPO) expression is increased in activated glia, and has been used as a marker of neuroinflammation in PET imaging. However, the extent to which TSPO upregulation reflects a pro‐ or anti‐inflammatory phenotype remains unclear. Our aim was to determine whether TSPO upre...
Main Authors: | Pannell, M, Economopoulos, V, Wilson, T, Kersemans, V, Isenegger, P, Larkin, J, Smart, S, Gilchrist, S, Gouverneur, V, Sibson, N |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Wiley
2019
|
Similar Items
-
Anti-Inflammatory Microglia/Macrophages as a Potential Therapeutic Target in Brain Metastasis
by: Andreou, K, et al.
Published: (2017) -
Factors ameliorate pro-inflammatory microglia polarization through inhibition of reactive astrocytes induced by 2-chloroethanol
by: Tong Wang, et al.
Published: (2023-08-01) -
Anti-inflammatory Microglia/Macrophages As a Potential Therapeutic Target in Brain Metastasis
by: Kleopatra E. Andreou, et al.
Published: (2017-10-01) -
Brivaracetam exhibits mild pro-inflammatory features in an in vitro astrocyte-microglia co-culture model of inflammation
by: Fatme Seval Ismail, et al.
Published: (2022-11-01) -
Resveratrol differentially modulates inflammatory responses of microglia and astrocytes
by: Lu Xiaofeng, et al.
Published: (2010-08-01)