The importance of the immunodominant CD8+ T cell epitope of Plasmodium berghei circumsporozoite protein in parasite- and vaccine-induced protection

The importance of the immunodominant CD8+ T cell epitope of Plasmodium berghei circumsporozoite protein in parasite- and vaccine-induced protection

The circumsporozoite protein (CSP) builds up the surface coat of sporozoites and is the leading malaria pre-erythrocytic-stage vaccine candidate. CSP has been shown to induce robust CD8+ T cell responses that are capable of eliminating developing parasites in hepatocytes, resulting in protective imm...

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Những tác giả chính:	Gibbins, MP, Müller, K, Glover, M, Liu, J, Putrianti, ED, Bauza, K, Reyes-Sandoval, A, Matuschewski, K, Silvie, O, Hafalla, JCR
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	American Society for Microbiology 2020

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