Investigation into the relationship between PARPs in DNA repair and synthetic lethality with homologous recombination deficiency

<p>The genome of each cell is under constant threat from various forms of DNA damage. In order to protect themselves from this danger, cells possess a number of pathways able to resolve DNA lesions. The addition of poly(ADPribose) is a post-translational modification produced by attaching succ...

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Bibliografiske detaljer
Hovedforfatter: Ronson, G
Andre forfattere: Lakin, N
Format: Thesis
Sprog:English
Udgivet: 2017
Fag: