TPC2 proteins mediate nicotinic acid adenine dinucleotide phosphate (NAADP)- and agonist-evoked contractions of smooth muscle.

TPC2 proteins mediate nicotinic acid adenine dinucleotide phosphate (NAADP)- and agonist-evoked contractions of smooth muscle.

Agonists such as those acting at muscarinic receptors are thought to induce contraction of smooth muscle primarily through inositol 1,4,5-trisphosphate production and release of Ca(2+) from sarcoplasmic reticulum. However, the additional Ca(2+)-mobilizing messengers cyclic adenosine diphosphate ribo...

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Detalles Bibliográficos
Main Authors: Tugba Durlu-Kandilci, N, Ruas, M, Chuang, K, Brading, A, Parrington, J, Galione, A
Formato: Journal article
Idioma:English
Publicado: 2010

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