Prion protein codon 129 polymorphism in mild cognitive impairment and dementia: the Rotterdam Study

Creutzfeldt–Jakob disease is a rare, fatal, neurodegenerative disease caused by the accumulation of abnormally folded prion proteins. The common polymorphism at codon 129 (methionine/valine) in the prion protein (PRNP) gene is the most important determinant of genetic susceptibility. Homozygotes of...

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書誌詳細
主要な著者: Karamujić-Čomić, H, Ahmad, S, Lysen, TS, Heshmatollah, A, Roshchupkin, GV, Vernooij, MW, Rozemuller, AJM, Ikram, MA, Amin, N, van Duijn, CM
フォーマット: Journal article
言語:English
出版事項: Oxford University Press 2020