Differential inhibition of membrane type 3 (MT3)-matrix metalloproteinase (MMP) and MT1-MMP by tissue inhibitor of metalloproteinase (TIMP)-2 and TIMP-3 rgulates pro-MMP-2 activation.
The membrane type (MT)-matrix metalloproteinases (MMPs) constitute a subgroup of membrane-anchored MMPs that are major mediators of pericellular proteolysis and physiological activators of pro-MMP-2. The MT-MMPs also exhibit differential inhibition by members of the tissue inhibitor of metalloprotei...
Main Authors: | Zhao, H, Bernardo, M, Osenkowski, P, Sohail, A, Pei, D, Nagase, H, Kashiwagi, M, Soloway, P, DeClerck, Y, Fridman, R |
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Format: | Journal article |
Language: | English |
Published: |
2004
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