Neutralizing interleukin-4 prevents transplant arteriosclerosis mediated by indirect pathway T cells under CD40-CD154 costimulation blockade.

INTRODUCTION: Blockade of the CD40-CD154 costimulatory pathway can prolong allograft survival, but does not prevent the development of transplant arteriosclerosis in several models. In this study, we investigated the mechanisms of CD40-CD154-independent transplant arteriosclerosis in major histocom...

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Autori principali: Spriewald, B, Ensminger, S, Bushell, A, Wood, K
Natura: Journal article
Lingua:English
Pubblicazione: 2008